Evidence map›Paper›PMID 42032348›Full record

ArticleMikrochimica acta2026

Fe/Mo-doped carbon dots as a bifunctional nanozyme for self-validating colorimetric and fluorometric sensing of hydroquinone.

Xiaoming Li, Qiu Mao, Lin He, Zhengwei Zhang, Dongmei Liu, Lu Liu, Pan Ju, Shijia Ding, Siqiao Li, Rong Luo

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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Xiaoming Li *The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Qiu Mao *Center for Medical Epigenetics, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, China.
Lin HeChongqing University Affiliated Fuling Hospital, Chongqing, 408000, China.
Zhengwei ZhangChongqing Research Center for Pharmaceutical Engineering, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China.
Dongmei LiuChongqing Research Center for Pharmaceutical Engineering, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China.
Lu LiuThe First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Pan JuThe First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Shijia DingKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Siqiao LiCenter for Medical Epigenetics, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, China. lsqzzw@cqmu.edu.cn.
Rong LuoThe First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. Firefly_1314@163.com.

Funding

National Natural Science Foundation of China 82372350Natural Science Foundation Project of Chongqing CSTB2025NSCQ-GPX1170Youth Project of Science and Technology Research Program of Chongqing Education Commission of China KJQN202300457Youth Project of Science and Technology Research Program of Chongqing Education Commission of China KJQN202400478
6 · The paper itself

Abstract

Bimetallic Fe/Mo-doped carbon dots (Fe/Mo-CDs) have been developed as a high-performance nanozyme to construct a self-validating dual-mode (colorimetric/fluorometric) platform for hydroquinone (HQ) detection. The Fe/Mo-CDs exhibited strong peroxidase-like activity, catalyzing H2O2-mediated TMB oxidation to generate oxTMB, which simultaneously yields a colorimetric signal and quenches the fluorescence of Fe/Mo-CDs through a confirmed FRET process. The introduction of HQ competitively scavenges the essential reactive oxygen species, inhibiting oxTMB formation and triggering synchronous signal inversion in both channels. This endogenous self-validating function enables favorable analytical performance, with wide linear ranges and ultralow detection limits (0.03 µM for colorimetric; 0.016 µM for fluorometric). Successful application in commercial creams with satisfactory recoveries underscores its strong potential for accurate and reliable screening in complex samples. This work not only presents a sensitive sensor for HQ but also offers a novel design strategy for developing intelligent, self-validating biosensing systems.

Indexed as

Carbon Quantum DotsColorimetryHydroquinonesBiosensing TechniquesCarbonFluorometryHydrogen PeroxideIronLimit of DetectionCarbonHydrogen PeroxidehydroquinoneHydroquinonesIronColorimetric and fluorometric detectionDual-mode sensingFe/Mo-doped carbon dotsHydroquinone detectionNanozyme

Identifiers

PMID42032348

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.