Evidence map›Paper›PMID 42032304›Full record

Reviewnpj biomedical innovations2026

Use of in vitro co-culture models to inform bacterial engineering for the treatment of solid tumours.

Sara Foschini, Josephine A Wright, Susan L Woods, Rebekah de Nys

Abstract readReview
In one paragraph

Review in npj biomedical innovations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara FoschiniCollege of Health, Adelaide University, Adelaide, SA, Australia.
Josephine A WrightCollege of Health, Adelaide University, Adelaide, SA, Australia.
Susan L WoodsCollege of Health, Adelaide University, Adelaide, SA, Australia.
Rebekah de NysCollege of Health, Adelaide University, Adelaide, SA, Australia. rebekah.denys@adelaide.edu.au.

Funding

Faculty of Health Science at the University of Adelaide Alfred and Ferrers Scammell Research Fellowship
6 · The paper itself

Abstract

Engineered bacterial therapeutics are emerging as promising candidates for the treatment of solid cancers. However, despite effectively reducing tumour burden in different pre-clinical models, these "smart bugs" are yet to convincingly translate this efficacy to cancer treatment in humans. Here, we highlight key features of in vitro co-culture methods and how they can be used to investigate bacterial behaviour and guide the rational engineering of more effective anti-cancer bacterial therapeutics.

Identifiers

PMID42032304
PMCPMC13055077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.