Evidence map›Paper›PMID 42032162›Full record

ArticleCommunications biology2026

Deciphering the multi-site phos-code of IRBIT underlying its binding to IP

Qing Lin, Hao Yang, Qi Feng, Tomohide Sumi, Kozo Hamada, Yi Qian, Fang Bai, Akihiro Mizutani, Katsuhiko Mikoshiba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qing Lin *Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China.
Hao Yang *Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0009-0008-0040-276X
Qi Feng *Shanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0009-0001-9981-8886
Tomohide SumiLab of Pharmacotherapeutics, Showa Pharmaceutical University, Tokyo, Japan.
Kozo HamadaShanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0000-0002-2795-802X
Yi QianShanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China.ORCID http://orcid.org/0000-0001-6376-0240
Fang BaiShanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China. baifang@shanghaitech.edu.cn.ORCID http://orcid.org/0000-0003-1468-5568
Akihiro MizutaniLab of Pharmacotherapeutics, Showa Pharmaceutical University, Tokyo, Japan. mizutani@ac.shoyaku.ac.jp.ORCID http://orcid.org/0000-0003-4155-802X
Katsuhiko MikoshibaShanghai Institute for Advanced Immunochemical Studies (SIAIS), ShanghaiTech University, Shanghai, China. mikosiba@shanghaitech.edu.cn.ORCID http://orcid.org/0000-0002-3487-6970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IRBIT has been previously shown to interact with the inositol 1,4,5-trisphosphate (IP

Indexed as

Eye ProteinsInositol 1,4,5-Trisphosphate ReceptorsAnimalsBinding SitesCalciumCasein Kinase IICyclic AMP-Dependent Protein KinasesHEK293 CellsHumansInositol 1,4,5-TrisphosphateLectins, C-TypeMembrane ProteinsPhosphorylationProtein BindingCalciumCasein Kinase IICLECL1 protein, humanCyclic AMP-Dependent Protein KinasesEye ProteinsInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsLectins, C-TypeMembrane Proteins

Identifiers

PMID42032162
PMCPMC13319452

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.