Evidence map›Paper›PMID 42032138›Full record

ArticleNPJ precision oncology2026

Cetuximab plus capecitabine every three weeks as first-line maintenance therapy for RAS/BRAF wild-type metastatic colorectal cancer: a phase Ib dose-escalation study.

Xiaoyu Xie, Ziqin Lin, Weiwei Li, Yuqian Xie, Jianwei Zhang, Huabin Hu, Shanshan Li, Xiaohui Zhai, Lishuo Shi, Yanhong Deng

Abstract read
In one paragraph

Article in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoyu XieDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Ziqin LinDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Weiwei LiDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Yuqian XieDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Jianwei ZhangDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Huabin HuDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Shanshan LiDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Xiaohui ZhaiDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Lishuo ShiClinical Research Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China.
Yanhong DengDepartment of Medical Oncology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China. dengyanh@mail.sysu.edu.cn.

Funding

Beijing Bethune Charitable Foundation 2021-YJ-088-JNational Natural Science Foundation of China 82272800National Science Fund for Distinguished Young Scholars 82425045Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0520304
6 · The paper itself

Abstract

Cetuximab plus fluoropyrimidine every two weeks (Q2W) is a common maintenance approach for RAS/BRAF wild-type metastatic colorectal cancer, but is limited by infusion burden and schedule misalignment. We conducted a phase Ib, nonrandomized 3 + 3 dose-escalation study evaluating cetuximab (400-700 mg/m

Identifiers

PMID42032138
PMCPMC13320180

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.