Evidence map›Paper›PMID 42032111›Full record

Reviewnpj biomedical innovations2025

Inflammation: a matter of immune cell life and death.

Elizabeth C Bender, Halah S Tareq, Laura J Suggs

Abstract readReview
In one paragraph

Review in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. The theory of the inflammatory ecosystem.Science China. Life sciences · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. LIN-23 AffectsbioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Unique/Rapid Feedback Mechanisms of PGDBioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  16. Article
  17. Box-Behnken Design Optimization of High-Pressure Processed Bitter Melon (International journal of molecular sciences · 2026
    Article
  18. Article
  19. Immunomodulatory Properties of the Cyclic Lipopeptide Surfactin.Journal of microbiology and biotechnology · 2026
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth C BenderDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.
Halah S TareqDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.
Laura J SuggsDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA. suggs@utexas.edu.

Funding

NIH HHS EB32211
6 · The paper itself

Abstract

Inflammation is triggered by an insult or injury to the cells of the body and is a healthy and productive step towards healing. Persistent inflammation, however, is a dysregulated response and can lead to a host of unwanted disease states. The death of cells by necrosis is known to initiate inflammation, while the programmed death of cells by apoptosis limits the inflammatory response. We propose here that there exists a spectrum of cell living, aging, dying, and death states that have differential effects on inflammatory disease.

Identifiers

PMID42032111
PMCPMC13055066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.