Articlenpj biomedical innovations2025
Towards adaptive bioelectronic wound therapy with integrated real-time diagnostics and machine learning-driven closed-loop control.
Article in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Artificial intelligence-guided nanozyme engineering for chronic wound healing: from rational design to precision therapeutics.Bioactive materials · 2027Review
- Dehydration-resistant multi-functional hydrogel-based iontophoretic drug delivery for wound healing.Nano convergence · 2026Article
- Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.Nano-micro letters · 2026Review
- Convergence of Soft Electronics and Artificial Intelligence: From Materials to Intelligent Systems.Nano-micro letters · 2026Review
- Advanced biomaterial strategies for cancerous wound management from palliative to multifunctional platforms.iScience · 2026Review
- Skin-like micropumps transform human motion into fluidic flow via morphing valves.Microsystems & nanoengineering · 2026Article
- A multi therapy bioelectronic wound dressing.npj biomedical innovations · 2026Article
- Materials and System Design for Self-Decision Bioelectronic Systems.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Deciphering skin architecture, wound pathophysiology and molecular mechanisms of healing: insights into immune response and therapeutic strategies.Frontiers in bioengineering and biotechnology · 2026Review
- Medical AI across Data Regimes to Promote Proactive Health.Health data science · 2026Review
- Development of a wireless bioelectronic actuator for wound healing in a porcine model.Scientific reports · 2025Article
- Accelerating Wound Healing Through Deep Reinforcement Learning: A Data-Driven Approach to Optimal Treatment.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors.
Funding
Abstract
Impaired wound healing affects millions worldwide, especially those without timely healthcare access. Here, we have developed a portable and wireless platform for real-time, continuous, and adaptive bioelectronic wound therapy (a-Heal). The platform integrates a wearable device for wound imaging and delivery of therapy with an ML Physician. The ML Physician analyzes wound images, diagnoses the wound stage, and prescribes therapies to guide optimal healing. Bioelectronic actuators in the wearable device deliver therapies, including electric fields or drugs, dynamically in a closed-loop system. a-Heal evaluates wound progress, adapts therapy as needed, and sends updates to human physicians through a graphical user interface, which also supports manual intervention. In preliminary studies using a large animal model, a-Heal promoted tissue regeneration, reduced inflammation, and accelerated healing, highlighting its potential in personalized wound care.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.