Evidence map›Paper›PMID 42032066›Full record

ArticleNature methods2026

PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities.

Ryan Fink, Shosei Imai, Nala Gockel, German Lauer, Kim Renken, Jonas Wietek, Paul J Lamothe-Molina, Falko Fuhrmann, Manuel Mittag, Tim Ziebarth and 15 more

Abstract read
In one paragraph

Article in Nature methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
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  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Ryan Fink *Neuromodulatory Circuits, Institute of Zoology, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0009-0001-2661-5586
Shosei Imai *Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0003-0388-4764
Nala GockelNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0009-0004-9464-0224
German LauerCellular Neurobiology, Department of Biology and Biotechnology, Ruhr University Bochum, Bochum, Germany.
Kim RenkenSynthetic Biology, University of Bremen, Bremen, Germany.
Jonas WietekCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Neuroscience Research Center, Berlin, Germany.ORCID http://orcid.org/0000-0002-8079-7042
Paul J Lamothe-MolinaInstitute of Pharmacology and Toxicology, University of Zürich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-7793-5133
Falko FuhrmannNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Manuel MittagNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Tim ZiebarthCellular Neurobiology, Department of Biology and Biotechnology, Ruhr University Bochum, Bochum, Germany.ORCID http://orcid.org/0000-0001-6673-198X
Annika CanzianiInstitute of Pharmacology and Toxicology, University of Zürich, Zurich, Switzerland.ORCID http://orcid.org/0009-0006-4051-8615
Martin KubitschkeSynthetic Biology, University of Bremen, Bremen, Germany.
Vivien KistmacherSystem Neurobiology, University of Bremen, Bremen, Germany.
Anny KretschmerNetwork Dysfunction, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Eva SebastianNeural Circuit Computation, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0003-3333-3197
Jana OttensSynthetic Biology, University of Bremen, Bremen, Germany.ORCID http://orcid.org/0009-0001-2500-4265
Dietmar SchmitzCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Neuroscience Research Center, Berlin, Germany.
Takuya TeraiDepartment of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-3425-3589
Jan GründemannNeural Circuit Computation, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0002-3149-0001
Sami I HassanSystem Neurobiology, University of Bremen, Bremen, Germany.
Tommaso PatriarchiInstitute of Pharmacology and Toxicology, University of Zürich, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-9351-3734
Andreas ReinerCellular Neurobiology, Department of Biology and Biotechnology, Ruhr University Bochum, Bochum, Germany.ORCID http://orcid.org/0000-0003-0802-7278
Martin FuhrmannNeuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0001-7672-2913
Robert E CampbellDepartment of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0003-0604-092X
Olivia Andrea MasseckNeuromodulatory Circuits, Institute of Zoology, University of Cologne, Cologne, Germany. omasseck@uni-koeln.de.ORCID http://orcid.org/0000-0002-1541-2388

Funding

High-Resolution Bidirectional Optical-Acoustic Mesoscopic Neural Interface for Image-Guided Neuromodulation in Behaving Animals - RF1 Admin SupplementRF1NS126102 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CAMPBELL, ROBERT E., RAZANSKY, DANIEL · 2022 to 2024
$3.1M
Deutsche Forschungsgemeinschaft (German Research Foundation) 184695641Deutsche Forschungsgemeinschaft (German Research Foundation) 394431587Deutsche Forschungsgemeinschaft (German Research Foundation) FOR 3004Deutsche Forschungsgemeinschaft (German Research Foundation) FOR3004Deutsche Forschungsgemeinschaft (German Research Foundation) MA4692/12-1Deutsche Forschungsgemeinschaft (German Research Foundation) MA4692/6-3Deutsche Forschungsgemeinschaft (German Research Foundation) SFB1089Deutsche Forschungsgemeinschaft (German Research Foundation) SFB1315Deutsche Forschungsgemeinschaft (German Research Foundation) SPP2395Deutsche Forschungsgemeinschaft (German Research Foundation) SPP2411EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 891959EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) MicroSynCom 865618MEXT | Japan Society for the Promotion of Science (JSPS) 19H05633MEXT | Japan Society for the Promotion of Science (JSPS) 24H00489MEXT | Japan Society for the Promotion of Science (JSPS) 24H02267MEXT | Japan Society for the Promotion of Science (JSPS) KAKENHI 21H00273NINDS NIH HHS RF1 NS126102
6 · The paper itself

Abstract

Genetically encoded calcium (Ca

Indexed as

CalciumLuminescent ProteinsAnimalsFluorescent Chemosensor CompoundsHumansMiceNeuronsOptogeneticsRed Fluorescent ProteinSignal-To-Noise RatioCalciumFluorescent Chemosensor CompoundsLuminescent ProteinsRed Fluorescent Protein

Identifiers

PMID42032066
PMCPMC13167472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.