Evidence map›Paper›PMID 42031958›Full record

ArticleNPJ precision oncology2026

A macrophage MHC-I axis links intratumoral heterogeneity to terminal CD8

Shangzhen Yin, Haiyan Gao, Qiang Li, Mengrui Wang, Peng Zhang, Yurou Guo, Pengyu Nan, Weihao Kong, Hongmei Shen, Liqiang Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shangzhen Yin *College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Haiyan Gao *Chinese Centre for Disease Control and Prevention, Centre for Endemic Disease Control, Harbin Medical University, Harbin, China.
Qiang Li *The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Mengrui WangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Peng ZhangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Yurou GuoCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Pengyu NanCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Weihao KongCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Hongmei ShenChinese Centre for Disease Control and Prevention, Centre for Endemic Disease Control, Harbin Medical University, Harbin, China. shenhm119@hrbmu.edu.cn.
Liqiang WangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China. wangliqiang@hrbmu.edu.cn.
Jianping LuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China. lujianping1992@163.com.

Funding

Basic Scientific Research Operating Expenses Research Project of Provincial Higher Education Institutions in Heilongjiang Province 2023-KYYWF-0270Heilongjiang Provincial Health Commission scientific research project, China YQJH2023051Heilongjiang Provincial Postdoctoral Science Foundation LBH-Z23227This work was supported by the National Natural Science Foundation of China 82373696
6 · The paper itself

Abstract

We integrated bulk, single-cell, and spatial transcriptomics to test whether intratumoral heterogeneity (ITH) aggravates CD8

Identifiers

PMID42031958
PMCPMC13319471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.