Evidence map›Paper›PMID 42031760›Full record

ArticleNature communications2026

Discovery of farnesal from a wild cucumber landrace enables eco-compatible biopesticide development against aphids.

Chunyu Suo, Lili Zhang, Qianwei Liang, Chaoyan Chen, Lei Qiu, Ziyi Li, Xinran Zhang, Xuewen Xu, Xiaohua Qi, Xuehao Chen and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Frontiers in veterinary science · 2026
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chunyu Suo *College of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.ORCID http://orcid.org/0009-0005-0984-7472
Lili Zhang *College of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Qianwei LiangCollege of Plant Protection, Yangzhou University, Yangzhou, P. R. China.
Chaoyan ChenCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Lei QiuCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Ziyi LiCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Xinran ZhangCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Xuewen XuCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Xiaohua QiCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.
Xuehao ChenCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China.ORCID http://orcid.org/0000-0002-5834-8750
Jianguo FengCollege of Plant Protection, Yangzhou University, Yangzhou, P. R. China. jgfeng@yzu.edu.cn.ORCID http://orcid.org/0000-0001-7324-0716
Xiaodong YangCollege of Horticulture and Landscape Architecture, Yangzhou University, Yangzhou, P. R. China. yxd@yzu.edu.cn.ORCID http://orcid.org/0000-0002-4971-2362

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32341043National Science Foundation of China | National Natural Science Foundation of China-Yunnan Joint Fund (NSFC-Yunnan Joint Fund) 32302534
6 · The paper itself

Abstract

Pest infestations devastate crop production, but chemical pesticides pose environmental and health risks. Eco-friendly biopesticides offer a solution, though limited by bioactive compound discovery. Here, we demonstrate that utilization of Yunnan's Xishuangbanna-a cucumber diversity hotspot-to identify the local variety XSBN032, which retains desirable agronomic traits under aphid pressure. Metabolomic and GC-MS analyses identify farnesal-a volatile compound significantly enriched in XSBN032-under infested and non-infested conditions. Applying 0.33 g/L farnesal nanoemulsion to cucumber leaves rapidly disrupts aphid metabolism (within 6 h), impairing amino acid pathways and suppressing growth/reproduction, achieving 74.9% mortality within 24 h while preserving plant photosynthesis. Significantly, this treatment demonstrates high environmental safety: 0% earthworm mortality (500 mg/L, 7 days) and negligible effects on natural enemies (0% ladybird mortality; 7.41% green lacewing mortality). Our study establishes an integrated pipeline-from resistant germplasm discovery to biopesticide development-providing a sustainable pest control strategy. Leveraging multi-omics screening and smart delivery systems holds promise for future eco-efficient biopesticides.

Indexed as

AphidsCucumis sativusFarnesolPest Control, BiologicalAnimalsGas Chromatography-Mass SpectrometryPlant LeavesFarnesol

Identifiers

PMID42031760
PMCPMC13319835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.