Evidence map›Paper›PMID 42031512›Full record

ArticleBritish journal of sports medicine2026

Resting and exercise-induced occult hypertension and coronary atherosclerosis in male masters endurance athletes.

Jamie O'Driscoll, Gemma Parry-Williams, Joanna Moser, Ioannis Vlahos, Daniel Obaid, Joyee Basu, Gherardo Finocchiaro, Saad Fyyaz, Hamish MacLachlan, Sarandeep Marwaha and 14 more

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Article in British journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jamie O'DriscollDiabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0002-5923-4798
Gemma Parry-WilliamsCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Joanna MoserDepartment of Radiology, St George's University Hospitals NHS Foundation Trust, London, UK.
Ioannis VlahosUniversity of Texas MD Anderson Cancer Centre Brain Tumor Centre, Houston, Texas, USA.
Daniel ObaidInstitute of Life Sciences, Swansea University Medical School, Swansea, UK.
Joyee BasuCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Gherardo FinocchiaroCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Saad FyyazCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Hamish MacLachlanCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.ORCID http://orcid.org/0000-0001-8682-6193
Sarandeep MarwahaCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Chris MilesCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Efstathios PapatheodorouCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Nicola GaibazziCardiologia Centro, Azienda Ospedaliero-Universitaria di Parma, Parma, Emilia-Romagna, Italy.
Domenico TuttolomondoCardiologia Centro, Azienda Ospedaliero-Universitaria di Parma, Parma, Emilia-Romagna, Italy.
Damini DeyBiomedical Imaging Research Institute, Cedars-Sinai, Los Angeles, California, USA.
Maximiliano MoreiraCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Athanasios BakalakosCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.
Thijs EijsvogelsDepartment of Medical BioSciences, Exercise Physiology Research Group, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0003-0747-4471
Vincent AengevaerenDepartment of Cardiology, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-8722-6739
Aneil MalhotraInstitute of Sport, Manchester Metropolitan University, Manchester, UK.ORCID http://orcid.org/0000-0002-8670-3764
Maria Tome-EstebanCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.ORCID http://orcid.org/0000-0002-8962-3524
Rajan SharmaSt George's University Hospitals NHS Foundation Trust, London, UK.
Michael PapadakisCardiovascular and Genomic Research Institute, City St George's University of London, London, UK.ORCID http://orcid.org/0000-0003-0616-2353
Sanjay SharmaCardiovascular and Genomic Research Institute, City St George's University of London, London, UK sasharma@citystgeorges.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent studies have demonstrated a greater prevalence of coronary atherosclerosis in male masters endurance athletes, but the underlying contributors remain unclear. We explored the relationship between occult resting and exercise-induced hypertension with coronary atherosclerosis characteristics.

methods198 male masters endurance athletes with a low Framingham risk score (<10%) and no clinical diagnosis of hypertension underwent 24-hour ambulatory blood pressure (ABP) monitoring and exercise BP assessment. Coronary CT angiography assessed coronary artery calcification (CAC) score, luminal stenosis and high-risk plaque features.

resultsSeventy-eight (39%) athletes were hypertensive on ABP monitoring and 93 (47%) demonstrated a hypertensive response to exercise. A CAC score of 1-99 Agatston units (AU), 100-399 AU and ≥400 AU was present in 94 (47%), 32 (16%) and 15 (8%) athletes, respectively. Twenty-four (12%) athletes had coronary stenoses >50%. Sixty-two athletes (31%) had calcified plaque, 32 (16%) had mixed plaque, 2 (1%) had non-calcified plaque and 26 (13%) had markers of high-risk plaque. Hypertension on ABP monitoring was significantly associated with a CAC score ≥100 AU (OR: 2.56; 1.08 to 6.04) and coronary stenosis >50% (OR: 2.92; 1.17 to 7.33). A hypertensive response to exercise was significantly associated with coronary stenosis >50% (OR: 4.72; 1.65 to 13.5) and the presence of high-risk plaque (OR: 3.27; 1.27 to 8.43).

conclusionMasters male endurance athletes have a high prevalence of occult hypertension, which is associated with high-risk features of coronary atherosclerosis. Both ambulatory and exercise-induced hypertension are associated with a higher prevalence of atherosclerotic coronary artery disease in male endurance athletes. Early identification and timely clinical management of this classic cardiovascular disease risk factor may reduce the burden of coronary atherosclerosis in athletes.

Indexed as

AthletesCoronary Artery DiseaseExerciseHypertensionRestBlood Pressure Monitoring, AmbulatoryComputed Tomography AngiographyHumansMaleMiddle AgedPhysical EndurancePlaque, AtheroscleroticRisk FactorsAthletesCardiologyExercise

Identifiers

PMID42031512
PMCPMC13479618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.