Evidence map›Paper›PMID 42030316›Full record

Trial reportPloS one2026

Acceptability of Suubi+Adherence intervention to improve ART adherence in Southern Uganda: A qualitative analysis.

Josephine Nabayinda, Ozge Sensoy Bahar, Phionah Namatovu, Proscovia Nabunya, Samuel Kizito, Anita Kabarambi, April Thames, Fred M Ssewamala

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03307226 (Suubi4Her), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03307226 nacompletednot on this map

Suubi4Her: A Combination Intervention Addressing HIV Risk Behaviors Among Older Adolescent Girls Transitioning Into Adulthood in Uganda

TypeinterventionalSponsorWashington University School of MedicineRan2018 to 2021Enrolled1,260ConditionsHIV/AIDSArmsYouth Development Accounts (YDA), YDA + Multiple Family Groups (MFG)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Josephine NabayindaWashington University in St. Louis Brown School, St. Louis, Missouri, United States of America.
Ozge Sensoy BaharNew York University Silver School of Social Work, New York, New York, United States of America.ORCID https://orcid.org/0000-0002-7230-0438
Phionah NamatovuInternational Center for Child Health and Development (ICHAD), Masaka Office, Masaka, Uganda.
Proscovia NabunyaWashington University in St. Louis Brown School, St. Louis, Missouri, United States of America.
Samuel KizitoNew York University Silver School of Social Work, New York, New York, United States of America.
Anita KabarambiWashington University in St. Louis Brown School, St. Louis, Missouri, United States of America.
April ThamesUniversity of California, Los Angeles, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, California, United States of America.
Fred M SsewamalaNew York University Silver School of Social Work, New York, New York, United States of America.

Funding

Suubi+Adherence-R2: Examining the longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthoodR01HD074949 · NICHD · WASHINGTON UNIVERSITY · PI NABUNYA, PROSCOVIA, SENSOY BAHAR, OZGE · 2012 to 2024
$7.7M
NICHD NIH HHS R01 HD074949
6 · The paper itself

Abstract

In Uganda, 150,000 young people were living with HIV by the end of 2023. While Antiretroviral therapy (ART) is effective in reducing HIV transmission, youth in SSA, including in Uganda, face greater challenges with ART adherence compared to adults. Poverty-focused interventions have been recommended to improve adherence and viral load suppression. In this manuscript from Suubi+Adherence-Round 2 study, we explored the acceptability of Suubi+Adherence, a combination intervention aimed at improving ART adherence among adolescents living with HIV in Uganda that was tested in a six-year longitudinal study called Suubi+Adherence (2012-2018). We conducted semi-structured in-depth interviews with 36 youths who participated in the Suubi+Adherence intervention, which comprised matched savings accounts, mentorship, financial management, and business development training. Interviews explored participants' motivations for joining, their experiences with the intervention, and the facilitators and barriers to intervention attendance. Informed by the Theoretical Framework of Acceptability, data were analyzed using thematic analysis and Dedoose software. Our results showed that the primary motivation for participation was the opportunity to learn about savings and income-generating activities. Participants also appreciated the Wisepill -an Electronic Monitoring Device, which reminded them to take their medication. Key facilitators for intervention attendance included transport reimbursements, family support, and content relevance. Challenges included long travel distances and associated costs, session timing conflicts with household responsibilities, and other personal obligations. Despite these challenges, participants highlighted the practical relevance of the intervention content, which aligned with their real-life experiences and needs. Our findings offer valuable insights into the acceptability of a combination intervention aimed at improving ART adherence among youth. These results have important implications for HIV treatment programs and policy in Uganda, particularly given the country's high HIV prevalence. The parent randomized clinical trial is registered in the clinical trials database (NCT03307226).

Indexed as

Anti-HIV AgentsHIV InfectionsMedication AdherenceAdherence InterventionsAdolescentFemaleHumansLongitudinal StudiesMaleQualitative ResearchUgandaViral LoadAnti-HIV Agents

Identifiers

PMID42030316
PMCPMC13108802

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.