Evidence map›Paper›PMID 42030034›Full record

ArticleBioMed research international2026

Potent Anticancer, Antimicrobial, and Anti-Inflammatory Activities of Boswellia sacra Extracted Oil Nanoemulgel.

Ahmad M Eid, Hani Naseef, Murad Abualhasan, Dana Yassin, Sally Jaber, Adan Abu Gazaleh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmad M EidDepartment of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0000-0002-3425-1321
Hani NaseefPharmacy Department, Faculty of Pharmacy Nursing and Health Professions, Birzeit University, Birzeit, State of Palestine, birzeit.edu.ORCID https://orcid.org/0000-0001-9700-8532
Murad AbualhasanDepartment of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus, State of Palestine, najah.edu.ORCID https://orcid.org/0000-0002-2083-856X
Dana YassinDepartment of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus, State of Palestine, najah.edu.
Sally JaberDepartment of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus, State of Palestine, najah.edu.
Adan Abu GazalehDepartment of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, An-Najah National University, Nablus, State of Palestine, najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBoswellia sacra (B. sacra), the chemical name for frankincense essential oil, is utilized extensively to treat multiple kinds of cancers as well as skin disorders like acne, infections, and inflammations. The goal of this project is to develop a nanoemulgel using B. sacra oil to enhance its antibacterial, anti-inflammatory, and anticancer effects. B. sacra oil was extracted from oleoresin gum.

methodsThe extracted oil was obtained via the steam distillation process. Then, nanoemulsion formulations were prepared using the self-nanoemulsifying technique with Tween 80 and Span 80, incorporating the selected nanoemulsion formula. The resulting nanoemulsion was then incorporated with Carbopol hydrogel to produce nanoemulgel.

resultsThe nanoemulsion showed a droplet size of 120.03 nm and a PDI below 0.3. The zeta potential for nanoemulgel was -35 mV at 0.4% Carbopol concentration, and the nanoemulgel formulation demonstrated pseudo-plastic behavior with no significant change in droplet size or PDI. The nanoemulgel has an antibacterial effect against various types of bacteria. The anticancer effect of B. sacra oil nanoemulgel was tested on different types of cancerous cells, which were: LX2, Hep-G2, Hela, MCF-7, and 3 T3, and the IC50 values were 186.2, 79.43, 186.2, 128.82, and 107.15 μg/mL, respectively. The IC

conclusionThe B. sacra oil nanoemulgel developed in this study has superior biological activities to those found in pure oil. Nanoemulgel is a promising delivery technique for improving several properties of pharmaceutical dosage forms.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsBoswelliaOils, VolatilePlant OilsAnti-Bacterial AgentsCell Line, TumorEmulsionsHumansNanoparticlesPlant ExtractsAnti-Bacterial AgentsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsEmulsionsOils, VolatilePlant ExtractsPlant Oilsanticanceranti-inflammatoryantimicrobialBoswellia sacrananoemulgelself-nanoemulsifying technique

Identifiers

PMID42030034
PMCPMC13108431

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.