Evidence map›Paper›PMID 42029977›Full record

ArticlePlant cell reports2026

Phytomelatonin receptor PMTR1 is crucial for melatonin-mediated plant broad-spectrum disease resistance.

Xiao Cheng, Yinghao Liu, Yu Zheng, Guoyin Liu, H Shi

Abstract read
PubMed Publisher
In one paragraph

Article in Plant cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in plant science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao ChengSanya Institute of Breeding and Multiplication, Key Laboratory of Biotechnology of Salt Tolerant Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan province, China.
Yinghao LiuSanya Institute of Breeding and Multiplication, Key Laboratory of Biotechnology of Salt Tolerant Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan province, China.
Yu ZhengSanya Institute of Breeding and Multiplication, Key Laboratory of Biotechnology of Salt Tolerant Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan province, China.
Guoyin LiuSanya Institute of Breeding and Multiplication, Key Laboratory of Biotechnology of Salt Tolerant Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan province, China. luxy1212@163.com.ORCID http://orcid.org/0009-0008-0393-864X
H ShiSanya Institute of Breeding and Multiplication, Key Laboratory of Biotechnology of Salt Tolerant Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou, Hainan province, China. sinthyjojo@163.com.

Funding

Hainan Province Science and Technology Special Fund No.ZDYF2024XDNY237Hainan Province Science and Technology Special Fund No.ZDYF2024XDNY241Medical Technology and Education of Zhejiang Province of China No.Qhyb2023-77National Natural Science Foundation of China No.32472569
6 · The paper itself

Abstract

key messagePMTR1 is essential for melatonin-improved plant broad-spectrum disease resistance to bacterial pathogens and viruses. Melatonin plays vital roles in various plant stress responses, and the identification of phytomelatonin receptor 1 (PMTR1) in recent decades further extends the phytomelatonin signaling pathway. However, whether and how PMTR1 participates in plant broad-spectrum disease resistance has remained unclear. Here, we confirmed that exogenous melatonin enhanced disease resistance to bacterial blight and mosaic disease, indicating the crucial role of melatonin in cassava broad-spectrum disease resistance. In addition, the transcription of MePMTR1 was induced by Xanthomonas axonopodis pv. manihotis (Xam), common mosaic virus (CMV) and exogenous melatonin, suggesting that MePMTR1 may be involved in cassava immunity. Further investigation illustrated that MePMTR1 was a positive regulator in disease resistance to Xam and CMV, and it was necessary for melatonin-improved broad-spectrum disease resistance to the bacterial pathogen and the virus. Moreover, RNA-sequencing identified many differentially expressed genes (DEGs) in melatonin-improved disease resistance through MePMTR1, including calmodulin-like proteins (CMLs), calmodulin-binding proteins (CaMBPs), transcription factors WRKYs and MYBs, respiratory burst oxidase homolog protein C (RBOHC), heat shock protein 20, pathogenesis-related protein (PR10), etc. In total, this study provides new light on the theoretical foundation of melatonin in modulating broad-spectrum disease resistance in cassava, extending the understanding of the melatonin signaling pathway in plant immunity.

Indexed as

Disease ResistanceManihotMelatoninPlant DiseasesPlant ProteinsGene Expression Regulation, PlantSignal TransductionXanthomonas axonopodisMelatoninPlant ProteinsBacterial pathogenBroad-spectrum disease resistanceMelatoninPhytomelatonin receptorVirus

Identifiers

PMID42029977

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.