ReviewCurrent neurology and neuroscience reports2026
When is the Radiologically Isolated Syndrome already Multiple Sclerosis According to the 2024 McDonald Criteria?
Review in Current neurology and neuroscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
purpose of reviewThe McDonald criteria assist neurologists in making accurate and timely diagnoses of multiple sclerosis (MS). The 2024 revision of these criteria aims to enable a more timely diagnosis by including additional biomarkers and alternative diagnostic approaches. They also extend to individuals with MRI findings typical of multiple sclerosis that lack classic MS symptoms, as they would previously have been classified as having radiologically isolated syndrome (RIS). This review examines the scientific foundation of the novel biomarkers used and how the revised criteria influence individuals undergoing diagnostic evaluation, clinical practice, and society. RECENT
findingsMost research concentrates on the scientific foundation for the updates rather than their impact. Benefits and potential disadvantages of the revised criteria can be identified for individuals undergoing diagnostic evaluation, clinical practice, and society. Additional guidelines for real-life application to guide management decisions are advisable.
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Registered trials
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