Evidence map›Paper›PMID 42029748›Full record

ReviewCurrent oncology reports2026

Polypharmacy, Medicine Optimisation, and Medication Adherence in Older Cancer Patients.

Abu Saleh Md Taher, Vanya Slavova-Boneva, Nicolò Matteo Luca Battisti

Abstract readReview
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In one paragraph

Review in Current oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abu Saleh Md TaherDepartment of Medicine, Breast Unit & Senior Adult Oncology Programme, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton , Surrey, SM2 5PT, UK.ORCID 0000-0002-3909-5356
Vanya Slavova-BonevaDepartment of Pharmacy & Senior Adult Oncology Programme, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey, SM2 5PT, UK.ORCID 0009-0004-5415-0300
Nicolò Matteo Luca BattistiDepartment of Medicine, Breast Unit & Senior Adult Oncology Programme, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton , Surrey, SM2 5PT, UK. nicolo.battisti@rmh.nhs.uk.ORCID 0000-0002-1063-1717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPolypharmacy is highly prevalent among elderly with cancer due to multimorbidity, supportive medications, and complex treatment regimens. It poses challenges of adverse drug reactions, drug–drug interactions, and adherence difficulties. This review explores the epidemiology, clinical consequences, and strategies for medication optimisation and adherence support in geriatric oncology. RECENT

findingsEmerging evidence demonstrates that pharmacist-led medication reviews, comprehensive geriatric assessment, and tools such as STOPP/START, Beers Criteria, and the FORTA list improve prescribing quality and facilitate deprescribing. Digital health interventions, including telemonitoring and connected pill systems, enhance adherence. Artificial intelligence and machine learning–based predictive models are beginning to identify patients at risk of adverse drug events or non-adherence, although integration into oncology work flows remains limited. Polypharmacy and non-adherence remain major barriers to optimal cancer care in older adults. Multidisciplinary optimisation, combined with digital and AI innovations, offers a pathway to safer and more effective treatment.

Indexed as

Antineoplastic AgentsDrug MonitoringMedication AdherenceNeoplasmsPolypharmacyAdherence InterventionsAgedDigital HealthDrug InteractionsDrug-Related Side Effects and Adverse ReactionsHumansAntineoplastic AgentsArtificial intelligenceDeprescribingDigital healthDrug-drug interactionGeriatric oncologyMedication adherenceMedication optimisationPolypharmacy

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.