ArticleJournal of the International Association of Providers of AIDS Care
Treatment Outcome, Medication Adherence, and Associated Factors After the Introduction of Dolutegravir-Based Antiretroviral Therapy (ART) Regimen Among HIV/AIDS Patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BackgroundThis study assessed treatment outcomes, medication adherence, and associated factors among human immunodeficiency virus (HIV) patients receiving dolutegravir-based antiretroviral therapy (ART) at Tikur Anbessa Specialized Hospital, Ethiopia.MethodsA hospital-based retrospective study was conducted from February to May 2024 using medical records of patients treated between 2018 and 2020. A total of 425 records were selected through random sampling. Sociodemographic, clinical, and treatment-related data were collected using a structured tool and analyzed with SPSS.ResultsAmong participants, 58.8% were female, and 76.0% were aged 31 to 60 years. Overall, medication adherence was 85.7%, and viral load suppression was achieved in 99.8% of patients. All patients were screened for tuberculosis, and 60% received isoniazid preventive therapy. Adherence was significantly associated with World Health Organization clinical stage, follow-up status, advanced HIV disease, and antiretroviral dose days.ConclusionDolutegravir-based ART showed excellent virologic outcomes and high adherence levels, highlighting key factors influencing treatment success.
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