Evidence map›Paper›PMID 42029595›Full record

ArticleMedical sciences (Basel, Switzerland)2026

Cognitive and Psychosocial Burden of Childhood Cancer Survivors in Greece: A Case-Control Study.

Kalliopi Mavrea, Katerina Katsibardi, Kleoniki Roka, Roser Pons, Vasiliki Efthymiou, Alexandros-Stamatios Antoniou, Antonios I Christou, Christina Kanaka-Gantenbein, George P Chrousos, Antonis Kattamis and 1 more

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Article in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kalliopi MavreaClinic for Assessment of Learning Difficulties, Center for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.
Katerina KatsibardiUniversity Oncology Hematology Unit, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.
Kleoniki RokaUniversity Oncology Hematology Unit, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.
Roser PonsPediatric Neurology Unit, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.
Vasiliki EfthymiouUniversity Research Institute for the Study of Genetic and Malignant Disorders in Childhood, Medical School, National and Kapodistrian University of Athens, 8 Levadeias Street, 11527 Athens, Greece.ORCID 0000-0002-3320-6588
Alexandros-Stamatios AntoniouFaculty of Primary Education, National and Kapodistrian University of Athens, 20 Ippokratous Street, 10680 Athens, Greece.
Antonios I ChristouDepartment of Special Education, University of Thessaly, 38221 Volos, Greece.ORCID 0000-0003-2981-1651
Christina Kanaka-GantenbeinClinic for Assessment of Learning Difficulties, Center for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.ORCID 0000-0001-6942-6470
George P ChrousosUniversity Research Institute for the Study of Genetic and Malignant Disorders in Childhood, Medical School, National and Kapodistrian University of Athens, 8 Levadeias Street, 11527 Athens, Greece.ORCID 0000-0002-3098-5264
Antonis KattamisUniversity Oncology Hematology Unit, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.ORCID 0000-0002-5178-0655
Flora BacopoulouClinic for Assessment of Learning Difficulties, Center for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Street, 11527 Athens, Greece.ORCID 0000-0003-1001-0926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo study the hypothesis that cognitive functions and learning skills are impaired in child/adolescent childhood cancer survivors (CCS). Secondary outcomes included psychosocial parameters and quality of life.

methodsThis case-control study was conducted over four years (2017-2021) at the largest pediatric Aghia Sophia Children's Hospital, in Greece. Eligible participants were children and adolescents in Greece. For CCS, ≥1 year should have elapsed from completion of cancer treatment. Assessments of neurocognitive function, learning and psychosocial skills and health-related quality of life (HRQoL) were performed with validated instruments (WISC-III, LAMDA software, Achenbach CBCL/6-18 and YSR, KIDSCREEN-52, respectively).

resultsIn total, 219 participants (47.49% males, mean age ± SD 11.72 ± 2.32 years), 70 CCS and 149 controls (matched for age, sex, family income), were included. Cases were CCS of acute lymphoblastic leukemia (

conclusionsCCS in Greece carry a significant burden of cognitive and psychological morbidity. Cognitive/educational and psychosocial support to CCS is imperative.

Indexed as

Cancer SurvivorsCognitionAdolescentCase-Control StudiesChildFemaleGreeceHumansMaleQuality of Lifecancercancer survivorscognitiveeducationGreeceintelligenceIQlearning difficultiespsychologicalquality of life

Identifiers

PMID42029595
PMCPMC13108100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.