Evidence map›Paper›PMID 42029484›Full record

ReviewVision (Basel, Switzerland)2026

Epidemiology of Keratoconus in India: A Systematic Review and Meta-Analysis of Indian Study Populations.

Matteo Ripa, Chiara Schipa, Paola Aceto, Sushad Prasad, Neeraj Apoorva Shah

Abstract readReview
In one paragraph

Review in Vision (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Aflibercept 8 mg for diabetic macular edema and neovascular age-related macular degeneration: an italian expert consensus paper.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matteo RipaDepartment of Ophthalmology, Sankara Eye Hospital, Jaipur 302039, Rajasthan, India.ORCID 0000-0001-7968-1336
Chiara SchipaCatholic University "Sacro Cuore", 00168 Rome, Italy.
Paola AcetoCatholic University "Sacro Cuore", 00168 Rome, Italy.ORCID 0000-0002-0228-0603
Sushad PrasadDepartment of Ophthalmology, Sankara Eye Hospital, Krishnankoil 626190, Tamil Nadu, India.
Neeraj Apoorva ShahDepartment of Ophthalmology, Sankara Eye Hospital, Jaipur 302039, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: To synthesize available evidence on the prevalence of keratoconus (KC) reported in Indian study populations and describe its demographic distribution. (2) Methods: PubMed, Embase, and Scopus were checked using free text and controlled vocabulary. A random-effect meta-analysis of pooled prevalence and its 95% confidence intervals (CIs) for KC among study participants recruited in India was conducted using exact binomial distributions and the Freeman-Tukey double-arcsine transformation. To identify potential sources of variability, we conducted subgroup analyses by dividing the data by geographic region, KC assessment, and study population. The methodological quality of each study was assessed using the Newcastle-Ottawa scale (NOS). Evidence quality was evaluated using the GRADE system. (3) Results: Across included studies, the total number of KC cases was 16,164, and sample sizes ranged from 152 to 2,384,523 participants. Prevalence estimates varied markedly across studies, reflecting substantial heterogeneity in study design, diagnostic criteria, and population characteristics. Most studies were conducted in high-risk clinical settings, limiting generalizability to the general population. Subgroup analyses showed no significant differences by geographic region or diagnostic modality (

Indexed as

incidenceIndiakeratoconusprevalencesystematic review and meta-analysis

Identifiers

PMID42029484
PMCPMC13108012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.