Evidence map›Paper›PMID 42028724›Full record

GuidelineThe international journal of neuropsychopharmacology2026

Responsible artificial intelligence integration framework for psychiatric guidelines.

Shlomo Mendlovic, Iryna Frankova, Eric Vermetten, Danuta Wasserman, Thomas G Schulze, Peter Falkai, Konstantinos N Fountoulakis, Kristina Adorjan, Hiroyuki Uchida, Eyal Fruchter and 2 more

Abstract readPractice Guideline
In one paragraph

Guideline in The international journal of neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shlomo MendlovicShalvata Mental Health Center, Hod Hasharon, Israel.
Iryna FrankovaDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Institute and World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eric VermettenDepartment of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.
Danuta WassermanThe World Psychiatric Association (WPA), Thônex, Geneva, Switzerland.
Thomas G SchulzeThe World Psychiatric Association (WPA), Thônex, Geneva, Switzerland.
Peter FalkaiDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.
Konstantinos N Fountoulakis3rd Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kristina AdorjanInstitute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.
Hiroyuki UchidaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-0628-7036
Eyal FruchterIcar Collective and Rappoport Medical Faculty, Technion, Haifa, Israel.
Gabriella GobbiNeurobiological Psychiatry Unit, Department of Psychiatry, McGill University and Research Institute, McGill University Health Center, Montréal, Québec, Canada.ORCID 0000-0003-4124-9825
Joseph ZoharSheba Medical Center, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0002-6925-9104

Funding

Canada Research Chair in Therapeutics for Mental Health
6 · The paper itself

Abstract

Artificial intelligence (AI) is reshaping medicine, promising advances in diagnosis, monitoring, and treatment, and psychiatry will be no exception. Yet the field remains fragmented: ethical guidelines, technical standards, and clinical workflows have evolved in parallel, creating uncertainty about how to integrate AI safely and meaningfully into psychiatric care. Existing frameworks often address isolated domains (explainability, data protection, or harm prevention [HP]) without providing a coherent structure that connects them to everyday clinical realities. This article introduces a global framework for the responsible integration of AI in psychiatry, built on 4 non-negotiable system capabilities: Explainable AI to ensure transparency and trust; Shared Decision-Making to protect patient autonomy; Electronic Health Record integration to secure continuity and accountability; and HP to embed multilayered safety controls. Together, these pillars define a responsibility-by-design approach that aligns technological development with psychiatry's ethical foundations. The framework offers clinicians, policymakers, and developers a roadmap for aligning innovation with human values and measurable improvements in clinical outcomes. By translating ethical commitments into auditable, non-negotiable system capabilities, it establishes a concrete foundation for regulatory oversight, guideline endorsement, and responsible AI deployment in psychiatry.

Indexed as

Artificial IntelligenceMental DisordersPsychiatryDecision Making, SharedElectronic Health RecordsHumansAIethicsguidelineintegrationpsychiatry

Identifiers

PMID42028724
PMCPMC13108442

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.