Evidence map›Paper›PMID 42028608›Full record

Observational studyJournal of oral rehabilitation2026

Temporomandibular Joint Involvement in Paediatric Patients Affected by Juvenile Idiopathic Arthritis.

Giulia Vallogini, Ambra Michelotti, Silvia Magni Manzoni, Paola Festa, Alessandra Putrino, Roberto Uomo, Lorenzo Maria Gregori, Simone Piga, De Benedetti Fabrizio, Angela Galeotti

Abstract readObservational Study
In one paragraph

Observational study in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia ValloginiDentistry Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Ambra MichelottiSchool of Orthodontics, University of Naples "Federico II", Naples, Italy.ORCID https://orcid.org/0000-0002-2969-2069
Silvia Magni ManzoniRheumatology Division, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Paola FestaDentistry Unit, AORN Santobono-Pausilipon, Naples, Italy.
Alessandra PutrinoDentistry Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Roberto UomoDentistry Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Lorenzo Maria GregoriDiagnostic Imaging Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Simone PigaClinical Pathways and Epidemiology Unit, Bambino Gesù Children's Hospital, Rome, Italy.
De Benedetti FabrizioRheumatology Division, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Angela GaleottiDentistry Unit, Bambino Gesù Children's Hospital, Rome, Italy.

Funding

Ministry of Health
6 · The paper itself

Abstract

backgroundJuvenile idiopathic arthritis (JIA) is an autoimmune disease that can involve the temporomandibular joint (TMJ).

objectivesTo investigate the association between clinical signs and symptoms of temporomandibular disorders (TMD) and TMJ inflammation, as detected by magnetic resonance imaging (MRI) in children and adolescents with JIA.

methodsMonocentric cross-sectional observational study. Consecutive JIA patients underwent clinical dental examination following the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and performed MRI examination when the presence of signs and/or symptoms was detected. TMJ involvement was assessed using MRI parameters. Data were analysed with descriptive statistics, using parametric statistical tests for normally distributed data and non-parametric statistical tests for other variables. Associations between TMD signs/symptoms and MRI findings were investigated using appropriate statistical tests. Adjustment for multiple comparisons was performed using a false discovery rate approach. A p-value < 0.05 after correction was considered statistically significant.

resultsSeventy-six JIA patients were included. In unadjusted analyses, multiple associations emerged between clinical findings and MRI signs of TMJ involvement. After correction for multiple comparisons, TMJ sounds remained significantly associated with protrusion limitation, and mandibular deviation patterns were significantly associated with inflammatory MRI findings, particularly synovial thickening and bone marrow edema. Other associations did not retain statistical significance after adjustment and should be considered exploratory.

conclusionsDental and TMD evaluations revealed correlations with MRI findings of TMJ involvement. Application of TMD screening at JIA onset might make it possible to detect TMJ-related early signs of arthritis in patients with JIA.

Indexed as

Arthritis, JuvenileTemporomandibular JointTemporomandibular Joint DisordersAdolescentChildCross-Sectional StudiesFemaleHumansMagnetic Resonance ImagingMalediagnostic criteria for temporomandibular disordersjuvenile idiopathic arthritismagnetic resonance imagingpaediatric patientstemporomandibular involvementtemporomandibular joint

Identifiers

PMID42028608
PMCPMC13358418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.