Evidence map›Paper›PMID 42028582›Full record

ArticleRespirology case reports2026

Positron Emission Tomography-Negative Mediastinal Lymph Node Metastasis From Clear Cell Renal Cell Carcinoma 11 Years After Nephrectomy Diagnosed by Endobronchial Ultrasound-Guided Transbronchial Needle Capillary Sampling.

Ryo Hara, Tomoyuki Araya, Takayuki Higashi, Hazuki Takato, Toshiyuki Kita

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryo HaraDepartment of Respiratory Medicine NHO Kanazawa Medical Center Kanazawa Japan.ORCID https://orcid.org/0009-0002-8073-0945
Tomoyuki ArayaDepartment of Respiratory Medicine NHO Kanazawa Medical Center Kanazawa Japan.ORCID https://orcid.org/0000-0001-9084-1628
Takayuki HigashiDepartment of Respiratory Medicine NHO Kanazawa Medical Center Kanazawa Japan.
Hazuki TakatoDepartment of Respiratory Medicine NHO Kanazawa Medical Center Kanazawa Japan.
Toshiyuki KitaDepartment of Respiratory Medicine NHO Kanazawa Medical Center Kanazawa Japan.ORCID https://orcid.org/0000-0001-6158-7683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old man was referred for evaluation of mediastinal lymphadenopathy. He had undergone right nephrectomy for clear cell renal cell carcinoma (ccRCC; pT3aN0M0, stage III) 11 years earlier and had remained recurrence-free without adjuvant therapy. Positron emission tomography/computed tomography (PET/CT) revealed an enlarged subcarinal lymph node which was non-FDG avid. Bronchoscopy was performed to obtain a pathological diagnosis. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) initially yielded bloody and inadequate specimens on rapid on-site cytologic evaluation (ROSE). The sampling technique was therefore switched to endobronchial ultrasound-guided transbronchial needle capillary sampling (EBUS-TBNCS), and ROSE demonstrated adequate cellular material with atypical cells. Histopathology and immunohistochemistry confirmed metastatic ccRCC. This case highlights that metastatic ccRCC should be considered in PET-negative mediastinal lymphadenopathy more than a decade after nephrectomy and that EBUS-TBNCS may facilitate diagnostic tissue acquisition when conventional EBUS-TBNA yields bloody specimens.

Indexed as

18F‐fluorodeoxyglucose positron emission tomography/computed tomography (18F‐FDG PET/CT)clear cell renal cell carcinoma (ccRCC)endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA)endobronchial ultrasound‐guided transbronchial needle capillary sampling (EBUS‐TBNCS)mediastinal lymphadenopathy

Identifiers

PMID42028582
PMCPMC13100484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.