ArticleContact in context2026
Rapid Quality Screening of Intra-lot Variability of Acetazolamide Using Near-Infrared Spectrometry.
Article in Contact in context, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Spectral Intra-Lot and Inter-Lot Variability in Methacholine.Contact in context · 2026Article
- Measuring Aztreonam Variations by Process Analytical Technology.Contact in context · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
Acetazolamide for Injection, USP is a sterile, preservative-free carbonic anhydrase inhibitor primarily indicated for the treatment of acute mountain sickness, fluid volume overload associated with heart failure, and elevated intraocular pressure in glaucoma. This research utilized Fourier transform near-infrared spectrometry (FT-NIR) to evaluate the intra-lot variability of 12 vials of Mylan Institutional Acetazolamide 500 mg. While all sampled vials appeared visually identical as white to yellowish-white powders, FT-NIR analysis identified significant spectral heterogeneity, particularly in the range of 4200 to 5200 cm
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.