ArticleJournal of ophthalmology2026
Rapid Plasma Reagin Tests of Serum, Cerebrospinal Fluid, and Aqueous Humor of Patients With Ocular Syphilis and AIDS.
Article in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Rapid Plasma Reagin Tests of Serum, Cerebrospinal Fluid, and Aqueous Humor of Patients With Ocular Syphilis and AIDS.Journal of ophthalmology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The diagnosis of ocular syphilis in patients with acquired immunodeficiency syndrome (AIDS) remains challenging. This study aimed to evaluate the potential utility of aqueous humor (AH) RPR testing as an adjunctive diagnostic tool for assessing clinical manifestations and visual function in AIDS-associated ocular syphilis. Methods: We conducted a retrospective observational cohort study of 31 patients (42 eyes) with ocular syphilis and AIDS treated at Beijing You'an Hospital between 2022 and 2025, based on comprehensive ophthalmic and systemic evaluations. Results: In patients with concurrent syphilis and AIDS, a higher pretreatment AH RPR reactivity level was associated with higher vitreous haze grades (OR = 4.10, 95% CI: 1.62-10.38, Conclusion: AH RPR can serve as a valuable adjunct for diagnosing ocular syphilis, as it indicates intraocular disease activity and informs treatment recommendations for the condition.
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