Engineering of the glucose uptake system to increase 2,4-Dihydroxybutyric acid production in

T A Stefanie Nguyen, Ceren Alkim, Nadine Ihle, Thomas Walther, Cláudio J R Frazão

Abstract read

In one paragraph

Article in Metabolic engineering communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

T A Stefanie NguyenChair of Bioprocess Engineering, Institute of Natural Materials Technology, TU Dresden, Bergstraße 120, 01062, Dresden, Germany.

Ceren AlkimToulouse Biotechnology Institute, UMR INSA-CNRS5504 and UMR INSA-INRAE 792, 135 avenue de Rangueil, 31077, Toulouse, France.

Nadine IhleChair of Bioprocess Engineering, Institute of Natural Materials Technology, TU Dresden, Bergstraße 120, 01062, Dresden, Germany.

Thomas WaltherChair of Bioprocess Engineering, Institute of Natural Materials Technology, TU Dresden, Bergstraße 120, 01062, Dresden, Germany.

Cláudio J R FrazãoChair of Bioprocess Engineering, Institute of Natural Materials Technology, TU Dresden, Bergstraße 120, 01062, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2,4-Dihydroxybutyric acid (DHB) is a promising C

Indexed as

13C metabolic flux analysis2,4-Dihydroxybutyric acidEscherichia coliGalactose permease (GalP)Metabolic engineeringPhosphotransferase system (PTS)

Identifiers

PMID42028332

DOI10.1016/j.mec.2026.e00276

PMCPMC13101720

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.