Evidence map›Paper›PMID 42028291›Full record

ArticleEClinicalMedicine2026

Pre-pregnancy weight in Swedish women and the risk of gestational diabetes and subsequent type 2 diabetes-a population-based cohort study.

Jon Edqvist, Annika Rosengren, Demir Djekic, Christina E Lundberg, Karin Andréasson, Pigi Dikaiou, Martin Adiels, Maria Åberg, Naveed Sattar, Carmen Basic and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Structural Characterisation ofMolecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jon EdqvistDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Annika RosengrenDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Demir DjekicDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Christina E LundbergDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Karin AndréassonDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Pigi DikaiouDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Martin AdielsDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Maria ÅbergSchool of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Naveed SattarSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Carmen BasicDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Teresia SvanvikRegion Västra Götaland, Department of Obstetrics and Gynaecology, Södra Älvsborgs Hospital, Borås, Sweden.
Martin LindgrenDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.
Erik ThunströmDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg SE 416 85, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity in young women is increasing. To which extent elevated pre-pregnancy overweight and obesity with and without gestational diabetes increase long-term risk of type 2 diabetes later in life has not been quantified. Methods: In a Swedish population-based cohort study we used data from the Swedish Medical Birth Registry in 1,153,074 primiparous women included in the registry between Jan 1, 1987 and Dec 31, 2019, with body mass index (BMI) at the first antenatal care visit as a proxy for pre-pregnancy weight to examine risk for gestational diabetes. We then compared women with gestational diabetes (n = 16,870) to age matched comparators (n = 81,862) and calculated hazards for developing type 2 diabetes identified from the National Diabetes registry over a median follow-up of 9 years. Findings: Among 1,153,074 women, 21,438 (1.9%) were diagnosed with gestational diabetes. Women with pre-pregnancy BMI > 35 kg/m Interpretation: Gestational diabetes serves as a stress test for developing type 2 diabetes, markedly amplifying risk in even women with normal pre-pregnancy weight, and with very high absolute rates in women with pre-pregnancy obesity. Future work should ascertain to which extent women with gestational diabetes have a structured follow-up after their pregnancy, and their subsequent prognosis. Funding: The Swedish Research Council; the Swedish governmental funding of clinical research (ALF); the Swedish Heart and Lung Foundation; and Diabetes Wellness.

Indexed as

Body mass indexEpidemiologyGestational diabetesGynaecologyType 2 diabetesWomen’s health

Identifiers

PMID42028291
PMCPMC13099346

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.