Evidence map›Paper›PMID 42028253›Full record

ArticleBiophotonics discovery2025

Skin tone corrected pulse oximetry models evaluated through reflective pulsatile Monte Carlo simulations.

Yan Tung Nicholas Chan, Megh Rathod, Daniel Franklin

Abstract read
In one paragraph

Article in Biophotonics discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yan Tung Nicholas ChanUniversity of Toronto, Faculty of Applied Science and Engineering, Division of Engineering Science, Toronto, Ontario, Canada.
Megh RathodTranslational Biology and Engineering Program, Ted Rogers Center for Heart Research, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-0776-798X
Daniel FranklinTranslational Biology and Engineering Program, Ted Rogers Center for Heart Research, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Skin tone bias in pulse oximetry is frequently reported to lead to overestimation of arterial blood oxygen saturation ( Aim: We aim to mitigate skin tone bias in pulse oximetry by integrating a melanin correction factor into the conventional ratio-of-ratios approach. We employ pulsatile Monte Carlo simulation to systematically map the "ratio of ratios" ( Approach: A six-layered skin model is implemented to approximate the microstructure of human skin, allowing diffuse reflectance computations through Monte Carlo methods. Pulsatile effects are captured by modeling diastolic and systolic phrases, facilitating the calculation of Results: Skin tone induced error is quantified and mitigated by incorporating a melanin correction factor into conventional ratio-of-ratios. The inclusion of a melanin-dependent variable results in a substantial reduction in skin tone bias. Conclusions: Monte Carlo simulations offer precise control over both melanin content and

Indexed as

arterial blood oxygen saturation correction modelsequitable patient careMonte Carlo simulationpulse oximetryskin tone bias

Identifiers

PMID42028253
PMCPMC13052488

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.