ArticleFrontiers in neurology
Does endolymphatic hydrops affect cochlear and vestibular nerve volumes? An MRI-based morphometric study.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Endolymphatic hydrops in patients with migraine: a correlative study.Frontiers in neurologyArticle
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5 authors.
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Abstract
Objective: To investigate the relationship between the severity of endolymphatic hydrops (EH) and volumetric changes in cochlear and vestibular nerves using high-resolution MRI, and to assess associations with clinical audiovestibular symptoms. Methods: A cohort of 108 patients with clinically and radiologically confirmed EH underwent 3 T MRI to obtain volumetric measurements of the cochlear and vestibular nerves. Nerve volumes were compared across EH grades using non-parametric statistics. Cochlear nerve volumes in affected and unaffected ears were compared in a subgroup with unilateral hearing loss. Associations between EH severity and symptoms (hearing loss, vertigo, tinnitus, aural fullness) were evaluated. Results: Cochlear nerve volumes did not differ significantly between EH grades ( Conclusion: EH severity does not significantly affect cochlear or vestibular nerve volumes measurable by MRI, nor does it strongly correlate with prevalence of clinical symptoms. These findings indicate that volumetric MRI, while reproducible and feasible, may have limited sensitivity as an imaging biomarker of EH. This underscores the need to explore alternative MRI-based structural or functional markers in future multimodal and longitudinal studies.
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