ArticlePNAS nexus2026
Entropy production bounds for systems running computer programs.
Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Mismatch cost (MMC) is a universally applicable lower bound on the entropy production (EP) of any fixed physical process across a given time interval. In the first part of the article, we establish results concerning MMC to prove that it scales at least linearly with the total heat flow in the worst case over initial distributions. We also prove that the MMC lower bound over a given time interval never decreases if the time interval is subdivided into a sequence of subintervals, and that the bound often increases. In the second part of the article, we introduce a general framework for computing the minimal EP (ie the MMC) associated with running a computer program on any physical system that implements a modern digital computer. We apply this general framework to compare MMC of running two canonical sorting algorithms, bubble sort and bucket sort. The framework enables us to investigate how thermodynamic cost depends on features like input size and structure (eg with or without repeated entries). Finally, we extend the framework to programs that call subroutines.
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