Evidence map›Paper›PMID 42028049›Full record

ArticleBiophotonics discovery2026

Influence of sample-specific properties on light scattering by human milk.

Wietske Verveld, Johanna Rebecca de Wolf, Nienke Bosschaart

Abstract read
In one paragraph

Article in Biophotonics discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wietske VerveldUniversity of Twente, Biomedical Photonic Imaging Group, Faculty of Science and Technology, Enschede, The Netherlands.ORCID https://orcid.org/0009-0006-3524-121X
Johanna Rebecca de WolfUniversity of Twente, Biomedical Photonic Imaging Group, Faculty of Science and Technology, Enschede, The Netherlands.ORCID https://orcid.org/0000-0003-4915-9648
Nienke BosschaartUniversity of Twente, Biomedical Photonic Imaging Group, Faculty of Science and Technology, Enschede, The Netherlands.ORCID https://orcid.org/0000-0001-9232-1079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Despite the numerous benefits of breastfeeding, many mothers quit breastfeeding early due to understudied lactation problems. Optical and photonic techniques provide promising, objective, and non-invasive methods for human milk analysis but require accurate characterization and modeling of light scattering in human milk. Aim: We aimed to describe the influences of sample-specific properties on the forward scattering coefficient of human milk samples. Approach: We composed an experimental dataset of 50 human milk samples, containing the scattering coefficient, fat concentration, serum refractive index, milk fat globule (MFG) refractive index, MFG size distribution, and refractive index and size distribution of non-fat particles per sample. We reconstructed scattering coefficients using Mie theory with sample-specific properties and compared them to experimental values. Results: This study confirmed a moderate correlation between experimental and reconstructed scattering coefficients when only the sample-specific fat concentration was considered (Spearman Conclusions: The sample-specific fat concentration and MFG size distribution are the most important parameters to consider when developing light scattering models of human milk.

Indexed as

human milkMie theoryoptical propertiesparticle sizingrefractive index.scattering

Identifiers

PMID42028049
PMCPMC13101067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.