Evidence map›Paper›PMID 42028013›Full record

ArticleiScience2026

Natural senolytic activity of

Ryo Furuuchi, Yohko Yoshida, Goro Katsuumi, Takaaki Furihata, Yusuke Joki, Chieh-Lun Hsiao, Masayoshi Suda, Hana Saito, Tamano Kumazaki, Hidefumi Makabe and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ryo FuruuchiAdvanced Research Institutes, Bourbon Corporation, Niigata 956-0841, Japan.
Yohko YoshidaDepartment of Advanced Senotherapeutics, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Goro KatsuumiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Takaaki FurihataDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Yusuke JokiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Chieh-Lun HsiaoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Masayoshi SudaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.
Hana SaitoDepartment of Agriculture, Graduate School of Science and Technology, Shinshu University, Kami-ina, Nagano 399-4598, Japan.
Tamano KumazakiDepartment of Agriculture, Graduate School of Science and Technology, Shinshu University, Kami-ina, Nagano 399-4598, Japan.
Hidefumi MakabeDepartment of Agriculture, Graduate School of Science and Technology, Shinshu University, Kami-ina, Nagano 399-4598, Japan.
Manabu AbeDepartment of Animal Model Development, Brain Research Institute, Niigata University, Niigata 951-8510, Japan.
Ippei ShimizuDepartment of Cardiovascular Aging, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 564-8565, Japan.
Tohru MinaminoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo 113-8431, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulation of senescent cells drives age-related diseases, and their removal (senolysis) has been reported to ameliorate pathological aging phenotypes. Here, we identified

Indexed as

Biological sciencesMolecular biologyPharmacology

Identifiers

PMID42028013
PMCPMC13101718

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.