ArticleFrontiers in surgery2026
Effect of dominant cement distribution zone on pain relief after unipedicular percutaneous vertebroplasty.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cement location within the vertebral body may influence pain relief after unipedicular vertebroplasty. We tested a simple four-zone classification of dominant intravertebral cement distribution in osteoporotic vertebral compression fractures. Methods: We retrospectively analyzed 425 patients treated from 2021 to 2024. On postoperative imaging, the vertebral body was divided into four equal zones (Zones 1-4) and the zone with the greatest cement accumulation was recorded. Pain was measured with the visual analog scale (VAS) before and after the procedure; change in VAS was the primary endpoint. Multivariable linear regression modeled change in VAS. Logistic regression modeled clinical response (change in VAS > 4). Results: Mean VAS decreased from 7.63 ± 0.84 to 3.31 ± 1.06 ( Conclusions: Dominant cement zone strongly predicts pain improvement after unipedicular vertebroplasty and may serve as a practical procedural quality marker.
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