ArticleFood science & nutrition2026
Monitoring Population Exposure to Low- and No-Calorie Sweeteners via Pooled Urine Analysis.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Low- and no-calorie sweeteners (LNCS) are increasingly used as sugar substitutes in processed foods and sweetened beverages to reduce energy intake while maintaining taste. Given that poor diet remains a major contributor to non-communicable diseases, LNCS offer a strategy to lower caloric intake. However, ongoing concerns about their health effects highlight the need for a clearer understanding of LNCS exposure patterns within vulnerable groups of the population. Data on LNCS exposure and consumption trends, especially in the younger population, remain limited. Pooled urine samples were analyzed for four LNCS (acesulfame, sucralose, cyclamate, and saccharin) using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). Urinary concentrations were determined for various demographics (sex, age, and remoteness) to identify patterns of exposure, with focus on the younger population (< 5 years). Measured concentrations across all pools (
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