Evidence map›Paper›PMID 42027722›Full record

ArticleJHLT open2026

Prognostic value of cardiopulmonary exercise testing parameters in young heart failure patients with moderately reduced exercise capacity.

Shotaro Komeyama, Osamu Seguchi, Makoto Murata, Nana Kitahata, Tasuku Hada, Hiroki Mochizuki, Hiroyuki Miura, Takuya Watanabe, Takuma Sato, Takeshi Kitai and 3 more

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In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shotaro KomeyamaDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Osamu SeguchiDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Makoto MurataDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Nana KitahataDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Tasuku HadaDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Hiroki MochizukiDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Hiroyuki MiuraDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Takuya WatanabeDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Takuma SatoDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Takeshi KitaiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Yasumasa TsukamotoDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Chisato IzumiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Norihide FukushimaDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Exercise capacity, evaluated using cardiopulmonary exercise testing (CPET), is an important prognostic factor in ambulatory heart failure (HF) patients. However, interpreting the results of CPET in young, ambulatory HF patients who tend to be optimistic about their prognosis is complicated. This study aimed to assess the clinical impact of CPET parameters in predicting the prognosis of young, ambulatory HF patients. Methods: This single-center retrospective observational study targeted young (≤50 years) HF patients with reduced ejection fraction (left ventricular ejection fraction ≤40%) and peak oxygen uptake (VO Results: A total of 113 patients (median age, 43 [35-47] years) were enrolled: of these, 45 (39.8%) experienced MACE (death, n = 2; admission for HF, n = 35; fatal arrhythmia, n = 8). Multivariate Cox regression analysis demonstrated age, plasma brain natriuretic peptide level, serum creatinine level, and ventilatory efficiency (VE/VCO Conclusions: Nearly 40% of young (≤50 years) HF patients with moderately reduced exercise capacity (peak VO

Indexed as

Cardiopulmonary exercise capacityHeart failureHeart transplantationLeft ventricular assist devicePeak oxygen uptakeVE/VCO2 slopeYoung

Identifiers

PMID42027722
PMCPMC13100253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.