Evidence map›Paper›PMID 42027656›Full record

ArticleF&S reports2026

First European live birth following uterine and adnexal transposition for fertility preservation: a case report and overview of reported neonatal outcomes.

Daniela Huber, Deborah Wernly

Abstract readCase Reports
In one paragraph

Article in F&S reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniela HuberDepartment of Gynecology and Obstetrics, Valais Hospital, Sion, Switzerland.
Deborah WernlyDepartment of Gynecology and Obstetrics, Valais Hospital, Sion, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report the first live birth in Europe, and the fifth worldwide, after uterine and adnexal transposition (UT) for fertility preservation in rectal cancer, and to review all published neonatal outcomes after UT. Design: Single-patient case report with comprehensive review of reported live births after UT. Subject: A 28-year-old nulliparous woman with locally advanced rectal adenocarcinoma (uT3 N1 cM0, pMMR/MSS). Exposure: Laparoscopic UT before pelvic chemoradiation, followed by uterine reimplantation during total mesorectal excision. Main Outcome Measures: Obstetric and perinatal outcomes, and placental histopathology. Results: The patient conceived naturally 18 months after uterine reimplantation. Pregnancy was complicated by intrauterine growth restriction (IUGR) and oligohydramnios, leading to elective cesarean delivery at 37 + 1 weeks of a healthy male newborn (2110 g; Apgar 9/10/10). Placental histology revealed maternal vascular malperfusion. Review of the four previously published live births confirmed natural conceptions, cesarean deliveries at 36-38 weeks, and uniformly favorable neonatal outcomes, although three pregnancies were complicated by IUGR. Conclusion: Successful pregnancy and live birth are achievable after UT and subsequent uterine reimplantation. These cumulative cases demonstrate that a temporarily displaced and later reimplanted uterus can sustain gestation to term. Given the observed risk of impaired fetal growth, enhanced third-trimester surveillance and routine placental examination are recommended. Uterine transposition represents a promising fertility-preservation option for young women requiring pelvic radiotherapy.

Indexed as

fertility preservationintrauterine growth restrictionlive birthrectal cancerUterine transposition

Identifiers

PMID42027656
PMCPMC13100844

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.