ArticleFrontiers in dental medicine2026
Evaluation of the effect of two biomimetic approaches on micro-tensile bond strength of one etch & rinse adhesive to dentin (An
Article in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Hydrolytic and enzymatic degradation of the resin-dentin interface compromises the longevity of adhesive restorations. Biomimetic strategies for guided dentin remineralization, including self-assembling peptide P11-4 (Curodont Repair™) and the polymer-induced liquid precursor (PILP) process using poly-L-aspartic acid, have been proposed to stabilize the collagen matrix and enhance adhesive bond durability. Methods: Fifty-four extracted human molars were artificially demineralized and randomly assigned to three pretreatment groups ( Results: Two-way analysis of variance revealed significant effects of pretreatment, storage time, and their interaction on µTBS values ( Conclusions: pretreatment with the self-assembling peptide P11-4 resulted in higher micro-tensile bond strength to demineralized dentin compared with the PILP approach at early storage periods. However, the durability of both biomimetic dentin remineralization strategies was time-dependent
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