ArticleFrontiers in nutrition2026
Comparing central venous access strategies in elderly patients with dysphagia: a survival analysis.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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- Erratum issued
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7 authors.
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Abstract
Background: Dysphagia in older adults often necessitates long term parenteral nutrition (TPN). However, the optimal central venous access strategy, including implantable central venous access port (ICVAP), non-tunneled central venous catheter (NT-CVC) or peripherally inserted central catheter (PICC), remains uncertain, particularly regarding survival and complication risk. Methods: This retrospective cohort study included 73 patients aged ≥65 years with dysphagia who received parenteral nutrition via ICVAP, NT-CVC, or PICC. Device selection was based on patient/family request and feasibility/acceptability at the discharge destination. Baseline characteristics were compared using ANOVA and chi-square/Fisher's exact tests, and standardized mean differences (SMD) were reported to quantify baseline imbalance. Survival was evaluated using Kaplan-Meier curves with log-rank tests. Multivariable Cox proportional hazards models were performed to adjust for predefined covariates. Short-term mortality and complications were compared using chi-square or Fisher's exact tests. Results: Survival differed significantly among the three groups (log-rank Conclusion: In this cohort of elderly patients with dysphagia receiving long-term parenteral nutrition, ICVAP use was associated with longer survival compared with NT-CVC, while no significant survival difference was observed between PICC and ICVAP. Given the retrospective design and non-random catheter selection, these findings should be interpreted as associations and warrant confirmation in prospective, multicenter studies incorporating standardized complication definitions and patient-centered outcomes.
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