ArticleKidney international reports2026
Evaluating Long-Term Outcomes Across eGFR Equations in Older Adults.
Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Introduction: The current diagnostic threshold for chronic kidney disease (CKD; estimated glomerular filtration rate [GFR; eGFR] < 60 ml/min per 1.73 m Methods: This cohort study used data from the aspirin in reducing events in the elderly (ASPREE) trial and its observational follow-up (ASPREE-eXtension). ASPREE enrolled community-dwelling older adults. Separate survival analyses compared the risk of reduced disability-free survival (DFS), its components, or major adverse cardiovascular events (MACE) between participants reclassified to a different CKD stage versus those who remained within the same stage when changing from CKD-EPI Results: Among 17,686 participants (mean age 75.1 ± 4.3 years), BIS1, and EKFC yielded eGFR values 12 to 15 ml/min per 1.73 m Conclusion: The use of older-age validated equations would substantially increase the prevalence of CKD but may not identify additional individuals at higher risk. These results suggest that current diagnostic thresholds may not be appropriate for older adults, particularly when applying older-age validated equations, and underscore the need to reconsider CKD definitions in the context of aging.
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