Evidence map›Paper›PMID 42027519›Full record

ArticleAnnals of thoracic surgery short reports2026

A 27-Year Comparative Analysis of Off-Pump and On-Pump Coronary Artery Bypass Grafting in Octogenarians.

Maria Comanici, Anoosha Nair, Kabeer Umakumar, Nandor Marczin, Sunil K Bhudia, Shahzad G Raja

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Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Maria ComaniciDepartment of Cardiac Surgery, Harefield Hospital, London, United Kingdom.
Anoosha NairDepartment of Cardiac Surgery, Harefield Hospital, London, United Kingdom.
Kabeer UmakumarDepartment of Cardiac Surgery, Harefield Hospital, London, United Kingdom.
Nandor MarczinDepartment of Anaesthesia and Critical Care, Harefield Hospital, London, United Kingdom.
Sunil K BhudiaDepartment of Cardiac Surgery, Harefield Hospital, London, United Kingdom.
Shahzad G RajaDepartment of Cardiac Surgery, Harefield Hospital, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Octogenarians are deemed a high-risk patient population with increased postoperative morbidity and mortality after conventional coronary artery bypass grafting with cardiopulmonary bypass. In such patients, reducing the invasiveness of the surgical procedure by avoiding cardiopulmonary bypass may improve outcomes. This study investigates the in-hospital outcomes, 30-day mortality, and long-term survival rates of off-pump coronary artery bypass (OPCAB) vs on-pump coronary artery bypass (ONCAB) in octogenarians and identifies significant preoperative predictors of long-term mortality. Methods: This retrospective cohort study included octogenarian patients who underwent either OPCAB or ONCAB, between January 1996 and September 2023, at our institution. In-hospital outcomes, 30-day mortality, and long-term survival during 20 years were compared between the groups. Propensity score matching was used to adjust for baseline differences. Statistical analyses included univariate and multivariate Cox regression analyses and Kaplan-Meier survival estimates. Results: Of 711 patients, 245 pairs were matched. Unmatched analysis showed that OPCAB had lower tracheostomy rates (1.5% vs 4.7%, Conclusions: OPCAB may reduce short-term mortality in octogenarians while providing comparable long-term survival to ONCAB. Surgical strategy should be individualized on the basis of preoperative risk profiles.

Identifiers

PMID42027519
PMCPMC13100803

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