Evidence map›Paper›PMID 42027480›Full record

ArticleAnnals of thoracic surgery short reports2026

Clinical, Quality, and Cost Outcomes of Patients With Early-Stage Non-Small Cell Lung Cancer Undergoing Surgery or Stereotactic Body Radiation Therapy.

Sowmyanarayanan Thuppal, Kanika Chawla, Ryan Bowman, Anthony Sleiman, Anthony Nestler, Daniel J Ferraro, C Matthew Bradbury, Stephen Markwell, Kristin Delfino, Stephen R Hazelrigg and 1 more

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sowmyanarayanan ThuppalDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Kanika ChawlaDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Ryan BowmanDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Anthony SleimanCenter for Clinical Research, Southern Illinois University School of Medicine, Springfield, Illinois.
Anthony NestlerDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Daniel J FerraroDepartment of Radiation Oncology, Southern Illinois University School of Medicine, Springfield, Illinois.
C Matthew BradburyDepartment of Radiation Oncology, Southern Illinois University School of Medicine, Springfield, Illinois.
Stephen MarkwellDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Kristin DelfinoCenter for Clinical Research, Southern Illinois University School of Medicine, Springfield, Illinois.
Stephen R HazelriggDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.
Traves D CrabtreeDivision of Cardiothoracic Surgery, Southern Illinois University School of Medicine, Springfield, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We evaluated how National Surgical Quality Improvement Program (NSQIP) risk, frailty, and quality of life influence treatment selection between surgery and stereotactic body radiotherapy (SBRT) in early-stage non-small cell lung cancer (NSCLC). Methods: Prospectively collected data from treatment-naive adults with early-stage NSCLC included demographics, pulmonary function, NSQIP risk scores, and frailty (index ≥3). Quality of life was assessed by Quality of Life Questionnaire Core 30, Quality of Life Questionnaire Lung Cancer 13, and modified Medical Research Council Dyspnea Scale tools. Results: SBRT was more likely for frail patients (odds ratio [OR], 4.92), those needing assistance (OR, 5.01), and those with disability (OR, 3.48) or impaired mobility (OR, 4.04). Multivariate analysis found that higher NSQIP mortality risk (OR, 12.60), frailty (OR, 4.80), and lower forced expiratory volume in 1 second predicted SBRT selection. Complications were more frequent after surgery (41% vs 17%; Conclusions: Frailty, NSQIP risk, and functional metrics help guide treatment selection in early-stage NSCLC. Surgery yields better survival and recurrence outcomes, whereas SBRT offers lower early morbidity and cost in selected patients.

Identifiers

PMID42027480
PMCPMC13100790

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.