Evidence map›Paper›PMID 42027476›Full record

ArticleAnnals of thoracic surgery short reports2026

Wedge Resection vs Stereotactic Body Radiation Therapy for Stage 1 Non-Small Cell Lung Cancer in Octogenarians.

Rolfy A Perez Holguin, William G Wong, Chan Shen, Matthew D Taylor, Michael F Reed, Pauline H Go

Abstract read
In one paragraph

Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rolfy A Perez HolguinDivision of Thoracic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
William G WongDivision of Thoracic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Chan ShenDivision of Outcomes, Research, and Quality, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Matthew D TaylorDivision of Thoracic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Michael F ReedDivision of Thoracic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Pauline H GoDivision of Thoracic Surgery, Department of Surgery, Pennsylvania State University College of Medicine, Hershey, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical resection is the mainstay of treatment for early-stage non-small cell lung cancer (NSCLC). Stereotactic body radiation therapy (SBRT) has been proposed as an alternative for older adult patients to avoid the morbidity associated with surgery. The aim of this study was to evaluate the 2 treatment modalities in octogenarians. Methods: The National Cancer Database was used to identify patients aged ≥80 years with clinical T1 N0 M0 NSCLC who underwent wedge resection or SBRT. Patients identified as medically inoperable were excluded. Propensity score matching was used to create a matched cohort. The Kaplan-Meier method and the multivariable Cox proportional hazards model were used to evaluate overall survival. Results: A total of 3938 patients met inclusion criteria. Propensity score matching yielded 137 well-balanced matched pairs. The unadjusted 5-year overall survival for the matched wedge resection group was 44.5%, compared with 20.1% for the SBRT group ( Conclusions: Compared with SBRT, wedge resection is associated with improved survival in octogenarian patients with clinical T1 N0 M0 NSCLC. Surgical resection allows for pathologic examination and lymph node sampling, which can lead to upstaging. Further investigation is warranted to identify the utility of SBRT for octogenarian patients.

Identifiers

PMID42027476
PMCPMC13100783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.