Evidence map›Paper›PMID 42027263›Full record

ArticleBrain & spine2026

Second edition of the recommendations from the Colombian consensus committee for the management of traumatic brain injury in the prehospital setting, emergency department, surgery, and intensive care (Beyond one option for treatment of traumatic brain injury: A stratified protocol [BOOTStraP]).

Andrés M Rubiano, Sandra Lorena Olaya, Christian O Ramírez, Enoc Noscue Montealegre, Kelly Johanna Arias Osorio, Jonathan Pardo Carranza, Julio César Diez Sepúlveda, Alfonso Bustamante Cristancho, Dumar Javier Figueredo Sanabria, José Luis Castillo García and 11 more

Abstract read
In one paragraph

Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Andrés M RubianoNIHR Global Health Research Group in Neurotrauma, University of Cambridge, UK/Neurosciences Institute, Universidad El Bosque, Bogotá, Colombia/Meditech Foundation, Cali, Colombia.
Sandra Lorena OlayaMEDITECH Foundation, Cali, Colombia.
Christian O RamírezColombian Association of Trauma and Emergency Medical Systems (ACTSEM), Colombia.
Enoc Noscue MontealegreColombian Association of Trauma and Emergency Medical Systems (ACTSEM), Colombia.
Kelly Johanna Arias OsorioColombian Association of Trauma and Emergency Medical Systems (ACTSEM), Colombia.
Jonathan Pardo CarranzaMEDITECH Foundation, Cali, Colombia.
Julio César Diez SepúlvedaColombian Association of Emergency Medicine Specialists (ACEM), Colombia.
Alfonso Bustamante CristanchoColombian Association of Emergency Medicine Specialists (ACEM), Colombia.
Dumar Javier Figueredo SanabriaColombian Association of Trauma and Emergency Medical Systems (ACTSEM), Colombia.
José Luis Castillo GarcíaVallesalud IPS, Cali, Colombia.
Juan Diego CiroColombian Association of Critical Care and Intensive Care Medicine (AMCI), Colombia.
Carlos Eduardo Rebolledo MaldonadoColombian Association of Critical Care and Intensive Care Medicine (AMCI), Colombia.
Berhioska Valentina Pérez VelásquezMEDITECH Foundation, Cali, Colombia.
Adrián Felipe Zapata LoperaColombian Association of Neurosurgery, Colombia.
William Ricardo Vargas EscamillaColombian Association of Neurosurgery, Colombia.
Carlos Felipe Salgado BelloColombian Association of Emergency Medicine Specialists (ACEM), Colombia.
Johanna Cecilia Valdeblanquez AtencioColombian Association of Neurosurgery, Colombia.
Wendy GonzálezMEDITECH Foundation, Cali, Colombia.
Andrés SalazarMEDITECH Foundation, Cali, Colombia.
Santiago Cardona-CollazosMEDITECH Foundation, Cali, Colombia.
Laura M Loaiza-CardonaMEDITECH Foundation, Cali, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Traumatic brain injury (TBI) remains a leading cause of mortality and disability in Colombia and other low- and middle-income countries (LMICs), where disparities in resource availability limit implementation of standardized care. The first edition of BOOTStraP (Beyond One Option for Treatment of Traumatic Brain Injury: A Stratified Protocol), published in 2020, provided guidance for TBI management across variable healthcare settings. Advances in neurotrauma care prompted development of an updated protocol. Research question: How can TBI management be optimized across prehospital care, emergency care, neurosurgical surgery, and intensive care phases in settings with varying resource availability? Material and methods: A multidisciplinary panel of 17 national experts in prehospital care, emergency medicine, neurosurgery, and intensive care conducted a structured consensus process using Delphi principles and Nominal Group Technique. Eleven predefined clinical questions were addressed. Recommendations were developed through subgroup work, literature review, and iterative voting, requiring ≥70% agreement at subgroup level and ≥90% plenary consensus. Final algorithms were stratified according to resource availability and healthcare complexity. Results: The second BOOTStraP edition produced 9 integrated management algorithms covering prehospital transport, emergency care, neurosurgical decision-making, and critical care. Interventions are stratified and color-coded by resource requirements, enabling feasible actions in low-, intermediate-, and high-resource settings. Algorithms integrate neuroprotection goals, triage criteria, surgical indications, and monitoring strategies. Discussion and conclusion: BOOTStraP provides a pragmatic, phase-based, resource-sensitive framework bridging evidence-based recommendations with real-world constraints. This approach supports context-adapted decision-making and may reduce secondary brain injury while improving standardization of TBI care in resource-limited environments.

Indexed as

Critical careEmergency carePractice guidelinePrehospital careResource-limited settingsTraumatic brain injury

Identifiers

PMID42027263
PMCPMC13101607

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.