SynthesisJournal of cosmetic dermatology2026
The Use of Microneedling With Exosomes in Dermatology: A Systematic Review.
Synthesis in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroneedling combined with exosome therapy has growing clinical relevance in dermatology. This systematic review will critically evaluate current evidence on the combined use of microneedling and exosomes in a number of dermatological diseases.
methodA systematic literature search was conducted using terms related to exosomes and microneedling using 3 databases in accordance with the Preferred Reporting Items for Systematic Reviews and synthesis (PRISMA) without meta-analyses (SWiM) guidelines. Studies were appraised using the JBI (Joanna Briggs Institute) Critical Appraisal tool.
resultsTwo hundred and fifty-six unique references were identified, and after screening, 10 studies were eligible for quality appraisal, after which 8 studies were selected for inclusion in the final narrative synthesis. Sample size of the studies ranged from 3 from 60 participants. The efficacy and side effect profiles of exosomes and microneedling were evaluated in the following dermatological conditions: androgenetic alopecia, skin aging, hyperpigmentation, active scarring, and enlarged pores.
conclusionMicroneedling and exosomes hold great promise in a range of dermatological conditions. This study highlights that more evidence is required before we can ascertain the safety profile and efficacy profile of microneedling and exosomes. Further investigation with longer follow-up periods and larger sample sizes is necessary to determine the long-term safety profile and effectiveness of this treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.