Evidence map›Paper›PMID 42026923›Full record

ArticleBioconjugate chemistry2026

Metabolic Glycoengineering Enables Fluorine-18 Radiolabeling of T Lymphocytes via Dual-Bioorthogonal Chemistry.

Anisa Biti, Alessia Centanni, Surachet Imlimthan, Heidi Harjunpää, Arina Sukhova, Susanne K Wiedmer, Susanna Fagerholm, Mirkka Sarparanta

Abstract read
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In one paragraph

Article in Bioconjugate chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anisa BitiDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.
Alessia CentanniDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.
Surachet ImlimthanDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.ORCID 0000-0003-2520-2146
Heidi HarjunpääDepartment of Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.ORCID 0000-0002-1380-9939
Arina SukhovaDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.
Susanne K WiedmerDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.ORCID 0000-0002-3097-6165
Susanna FagerholmDepartment of Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
Mirkka SarparantaDepartment of Chemistry, Faculty of Science, University of Helsinki, 00560 Helsinki, Finland.ORCID 0000-0002-2956-4366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to track therapeutic cells is critical for advancing adoptive cell therapy. Positron emission tomography (PET) offers sensitive, quantitative imaging, but improved strategies for cell labeling remain needed. Here, we report a metabolic glycoengineering approach that installs azide groups onto the Jurkat T lymphocyte surface using the canonical tetraacetylated

Indexed as

Fluorine RadioisotopesHexosaminesT-LymphocytesAnimalsAzidesCycloaddition ReactionHumansIsotope LabelingJurkat CellsMicePositron-Emission TomographyTissue DistributionAzidesFluorine-18Fluorine RadioisotopesHexosaminesN-azidoacetylmannosamine

Identifiers

PMID42026923
PMCPMC13195574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.