Evidence map›Paper›PMID 42026920›Full record

ReviewAngewandte Chemie (International ed. in English)2026

Recent Trends in Metabolomics by NMR Spectroscopy.

Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. UntargetedNutrients · 2026
    Trial
  2. QuantitativeMolecules (Basel, Switzerland) · 2026
    Review
  3. Article
  4. LongitudinalFrontiers in molecular biosciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giorgio Di PacoDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.
Gaia MeoniDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0002-8608-4641
Veronica GhiniDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0003-3759-6701
Alessia VignoliDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0003-4038-6596
Leonardo TenoriDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0001-6438-059X
Paola TuranoDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0002-7683-8614
Claudio LuchinatDepartment of Chemistry, "Ugo Schiff", University of Florence, Via della Lastruccia, Sesto Fiorentino, Florence, Italy.ORCID 0000-0003-2271-8921

Funding

MUR-Dipartimenti di Eccellenza 2023-2027 DICUS 2.0MUR-FIS 2 call, project "Benchtop NMR: Translating Metabolomics from High-Tech Laboratories to Point-of-Care Diagnostics (BONSAI)" FIS-2023-00334National Recovery and Resilience Plan, M4C2 Investment 1.3 - Research Program PE8 Project Age-It: "Ageing Well in an Ageing Society" CUP B83C22004800006PAN-HUB 2021-T4-AN-07-CUP B93C22000920001
6 · The paper itself

Abstract

This review is an update of our previous contribution published in Angewandte Chemie in January 2019 and provides a critical analysis of the overall scientific production and key findings from NMR-based metabolomics between January 2018 and April 2025. We developed a strategy (described in the Methodological Approach section) for systematically analyzing the literature that enabled us to identify 5081 studies published during this observation period. Descriptive statistics were used to summarize this large dataset in terms of frequency distribution of certain experimental parameters (e.g., magnetic field, pulse sequences, NMR active nuclei, etc.) and to identify six broad main fields of application: human health, food and nutrition, veterinary, plants, environment and analytical methods. The major one remains human health; in absolute terms, its share is greater than the sum of the other five. Within each field, we focused on a few key topics and, for each of them, we provided a detailed and critical analysis of the three articles that have received the largest number of citations per year.

Indexed as

MetabolomicsAnimalsHumansMagnetic Resonance Spectroscopyliterature analysismetabolomicsNMR spectroscopyresearch trends

Identifiers

PMID42026920
PMCPMC13245614

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.