Evidence map›Paper›PMID 42026913›Full record

ArticleImmunity, inflammation and disease2026

Effect of Respiratory Syncytial Virus on the Global Burden of Lower Respiratory Infections: Lessons From the Global Burden of Disease Study 1990-2021.

Jiafen Zhao, Tao Zhou, Cheng Jiang, Feng Peng

Abstract read
In one paragraph

Article in Immunity, inflammation and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiafen ZhaoDepartment of Rehabilitation, Xiantao First People's Hospital, Xiantao, China.
Tao ZhouDepartment of Gastroenterology and Hepatology, Huanggang Hospital of Traditional Chinese Medicine, Hubei University of Chinese Medicine, Huanggang, China.
Cheng JiangDepartment of Respiratory Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine/Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Feng PengDepartment of Pediatric, Xiangyang Hospital of Traditional Chinese Medicine (Xiangyang Institute of Traditional Chinese Medicine), Hubei University of Chinese Medicine, Xiangyang, China.ORCID https://orcid.org/0009-0009-0345-5063

Funding

Hubei Provincial Administration of Traditional Chinese Medicine General ZY2025L271Hubei Provincial Natural Science Foundation General Project 2024AFB908Hubei Provincial Natural Science Foundation Joint 2025AFD115
6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is a major cause of lower respiratory infections (LRIs), especially in children, the elderly, and immunocompromised individuals.

methodsUsing GBD 1990-2021 data, we analyzed global RSV-related LRI deaths and DALYs. Trends were assessed via age-standardized rates and joinpoint regression. We also examined regional and demographic disparities and their association with the Sociodemographic Index (SDI).

resultsIn 2021, RSV-related LRIs caused 31,525.1 deaths and 2.59 million DALYs globally, marking a 78.9% decrease since 1990. The greatest decline occurred between 2020 and 2021. South Asia and Sub-Saharan Africa showed the highest burden. Children under 5 and the elderly (80+) were most affected, particularly males. A negative correlation was observed between SDI and disease burden.

conclusionsRSV burden has declined, but remains high in low-SDI regions. Sustained public health efforts and vaccination are critical to further reduce impact.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsAged, 80 and overChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansInfantMaleDALYsdisease burdenGBD 2021lower respiratory infectionsrespiratory syncytial virus

Identifiers

PMID42026913
PMCPMC13106949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.