Evidence map›Paper›PMID 42026897›Full record

ArticleRespirology (Carlton, Vic.)2026

Right Atrial Pressure/Pulmonary Artery Wedge Pressure Ratio Correlates With Early Outcomes After Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension.

Cze Ci Chan, Bárbara Lacerda Teixeira, Angela Bautista, Melissa D Stinson, Thao T Drcar, Jenny Z Yang, Mona Alotaibi, Timothy M Fernandes, Demosthenes G Papamatheakis, David S Poch and 3 more

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Article in Respirology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cze Ci ChanDivision of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan City, Taiwan.ORCID https://orcid.org/0009-0005-8045-5041
Bárbara Lacerda TeixeiraDepartment of Cardiology, Hospital de Santa Marta, Unidade Local de Saúde São José, Lisbon, Portugal.
Angela BautistaDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Melissa D StinsonDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Thao T DrcarDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Jenny Z YangDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Mona AlotaibiDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Timothy M FernandesDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Demosthenes G PapamatheakisDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.ORCID https://orcid.org/0000-0001-8956-2357
David S PochDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Kim M KerrDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.
Michael M MadaniCardiovascular & Thoracic Surgery, San Diego Health System, University of California, San Diego, La Jolla, California, USA.
Nick H KimDivision of Pulmonary, Critical Care and Sleep Medicine, San Diego Health System, University of California, La Jolla, California, USA.ORCID https://orcid.org/0000-0003-4702-650X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe expected right atrial pressure (RAP) to pulmonary arterial wedge pressure (PAWP) ratio is < 1. Inversion of this ratio (RAP ≥ PAWP) has been linked to poor outcomes in pulmonary arterial hypertension, but its relevance in chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. For patients undergoing pulmonary endarterectomy (PEA), this ratio may be associated with postoperative outcomes and guide postoperative management.

methodsWe retrospectively reviewed consecutive CTEPH patients who underwent PEA at the University of California San Diego from January 2021 to December 2023. RAP/PAWP ratios ≥ 1 and < 1 were compared for postoperative outcomes. Haemodynamic data were derived from preoperative right heart catheterization. Outcomes included reperfusion pulmonary edema (RPE), ventilator days, re-intubation, ICU and hospital length of stay (LOS), and 30-day mortality.

resultsA total of 462 CTEPH patients met study criteria. Of these, 128 (27.7%) were in the inverse group (RAP/PAWP ≥ 1) and 334 (72.3%) in the control group (RAP/PAWP < 1). The inverse group had worse baseline functional class, cardiac index, NT-proBNP, and more haemoptysis. Postoperatively, rates of RPE (14% vs. 6%, p = 0.005) and re-intubation (5% vs. 1%, p = 0.036) were higher in the inverse group. They also required more ventilator days (2 vs. 1, p < 0.001) and had longer ICU (4 vs. 3 days, p = 0.002) and hospital LOS (13 vs. 11 days, p < 0.001). Thirty-day mortality was numerically higher in the inverse group (3% vs. 1%), though not statistically significant (p = 0.080).

conclusionRAP/PAWP ratio > 1 prior to PEA surgery was associated with higher rates of early postoperative complications.

Indexed as

Atrial PressureEndarterectomyHypertension, PulmonaryPulmonary EmbolismPulmonary Wedge PressureAgedChronic DiseaseFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsPulmonary ArteryRetrospective StudiesTreatment Outcomechronic thromboembolic pulmonary hypertensionhaemodynamicsoutcomespostoperative complicationspulmonary endarterectomy

Identifiers

PMID42026897
PMCPMC13432651

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.