Evidence map›Paper›PMID 42026895›Full record

SynthesisDevelopmental medicine and child neurology2026

Outcomes of children and young people with cerebral palsy receiving long-term respiratory support: A systematic review.

Rajkumar Dhandayuthapani, Alasdair Campbell, Catherine M McDougall, Florian Gahleitner, Steve Cunningham, Don S Urquhart

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajkumar DhandayuthapaniDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.ORCID https://orcid.org/0000-0002-8626-030X
Alasdair CampbellCommunity Paediatrics, Royal Hospital for Children and Young People, Edinburgh, UK.
Catherine M McDougallDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Florian GahleitnerDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Steve CunninghamDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Don S UrquhartDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo systematically review the current knowledge gap in, and impact of, long-term respiratory support in children and young people (CYP) with cerebral palsy (CP).

methodWe searched six databases from inception until 30th January 2025. Grey literature was also searched. Screening and data extraction using Covidence software, quality of evidence (Risk Of Bias In Non-randomized Studies - of Interventions), and certainty of evidence (Grading of Recommendation, Assessment, Development and Evaluation) grading were independently conducted by two reviewers, with a third reviewer resolving any lack of consensus.

resultsTitle and abstract screening (n = 1994) and full-text reviews (n = 45) identified four studies (with moderate to severe risk of bias) for data extraction. Findings presented as a narrative synthesis from vote counting suggest improvement in sleep study parameters for CYP with CP on long-term respiratory support and quality of life for their parents (low certainty of evidence).

interpretationThis review identified a significant knowledge gap in the use of long-term respiratory support in CYP with CP and its impact on health-related outcomes for such young people. This limits the information that can be offered when counselling parents/carers before initiating respiratory support in CYP with CP. Further research is needed to allow better service-planning at national and local levels.

Indexed as

Cerebral PalsyAdolescentChildHumansQuality of Life

Identifiers

PMID42026895
PMCPMC13649304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.