Evidence map›Paper›PMID 42026829›Full record

ArticlePharmacology research & perspectives2026

Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HT

Brittany M Brems, Erin E Sullivan, Ryan P McGlynn, Praveen Kulkarni, Craig F Ferris, Raymond G Booth

Abstract read
In one paragraph

Article in Pharmacology research & perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HTPharmacology research & perspectives · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brittany M BremsCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.ORCID 0009-0001-0395-8500
Erin E SullivanCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.ORCID 0009-0005-2745-3653
Ryan P McGlynnCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0001-9293-5441
Praveen KulkarniCenter for Translational Neuroimaging, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0002-8876-4544
Craig F FerrisDepartment of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0001-9744-5214
Raymond G BoothCenter for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0003-2349-6400

Funding

Delineating the role of serotonin 5-HT2 receptors in opioid use disorders:Development of novel 5-HT2 modulators with translational studies in rodents andprimatesR01DA047130 · NIDA · NORTHEASTERN UNIVERSITY · PI BOOTH, RAYMOND G., KOHUT, STEPHEN JOHN · 2018 to 2022
$3.2M
Training Program on Development of Medications for Substance Use DisorderT32DA055553 · NIDA · NORTHEASTERN UNIVERSITY · PI Raymond G. Booth, Alexandros Makriyannis · 2022 to 2026
$1.3M
NIDA NIH HHS R01 DA047130NIDA NIH HHS R01DA047130NIDA NIH HHS T32 DA055553NIDA NIH HHS T32DA055553U.S. Department of Defense W81XWH-15-0247U.S. Department of Defense W81XWH-17-1-0322
6 · The paper itself

Abstract

Serotonin (5-hydroxytryptamine, 5-HT) type-1 G protein-coupled receptors are expressed throughout the central nervous system. 5-HT

Indexed as

BrainSerotonin 5-HT1 Receptor AgonistsTetrahydronaphthalenesAnimalsMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLMice, KnockoutReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT1BWakefulnessReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT1BSerotonin 5-HT1 Receptor AgonistsTetrahydronaphthalenesaminotetralinawake animal imagingBOLDFPTNLX‐112phMRIserotonin receptor

Identifiers

PMID42026829
PMCPMC13106894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.