Evidence map›Paper›PMID 42026769›Full record

ArticleMagnetic resonance in medicine2026

Repeatability of Metabolic Imaging With Hyperpolarized Pyruvate: Back-to-Back Neuroimaging and Blood Analysis.

Jun Chen, Sung-Han Lin, Jessica Sudderth, Kelley A Derner, Crystal E Harrison, Maheen Zaidi, Jeannie D Baxter, Jeff Liticker, Zohreh Erfani, Craig R Malloy and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jun ChenAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sung-Han LinAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-1384-4037
Jessica SudderthChildren's Research Institute, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kelley A DernerAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Crystal E HarrisonAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Maheen ZaidiAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeannie D BaxterAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeff LitickerAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Zohreh ErfaniAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Craig R MalloyAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-5077-0642
Marco C PinhoDepartment of Radiology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ralph J DeBerardinisChildren's Research Institute, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jae Mo ParkAdvanced Imaging Research Center, the University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-7404-6971

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeff G McDonald · 2022 to 2026
$7.4M
Pyruvate and acetate metabolism after TBI: implications for cerebral energy metabolismR01NS107409 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI PARK, JAE MO · 2020 to 2024
$2.7M
Development of early metabolic imaging biomarkers for muscular dystrophy and cardiomyopathy in patientsR01HL170039 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI PRADEEP P.A. MAMMEN, Jae Mo Park · 2024 to 2026
$2.2M
A Clinical MR Scanner for Imaging Hyperpolarized Carbon-13S10RR029119 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2011 to 2011
$2.2M
A liquid helium-free preclinical polarizer for hyperpolarized 13C metabolic imagingS10OD028490 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI WANSAPURA, JANAKA · 2020 to 2020
$600k
NCRR NIH HHS S10RR029119NHLBI NIH HHS R01HL170039NIBIB NIH HHS P41EB015908NIDDK NIH HHS P30DK127984NIH Office of the Director S10OD028490NINDS NIH HHS R01NS107409U.S. Army Medical Research Acquisition Activity HT94252510616U.S. Army Medical Research Acquisition Activity W81XWH2210485
6 · The paper itself

Abstract

purpose

methodsSixteen healthy adults (mean age, 39.0 ± 15.9 years; 8 men) underwent blood sampling or MRI. Eight participants received bolus injections of non-hyperpolarized [1-

resultsPlasma

conclusionConsecutive injections of hyperpolarized [1-

Indexed as

BrainMagnetic Resonance ImagingNeuroimagingPyruvic AcidAdultCarbon IsotopesFemaleHumansLactic AcidMaleMiddle AgedReproducibility of ResultsYoung AdultCarbon IsotopesLactic AcidPyruvic Acidhyperpolarized pyruvatelactate clearanceneuroimagingrepeatability

Identifiers

PMID42026769
PMCPMC13269210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.