Evidence map›Paper›PMID 42026650›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Mind the gap: obtaining reliable sleep estimates and the diagnostic value of sleep discrepancy in individuals with Alzheimer's disease and Lewy body disease.

Victoria Grace Gabb, Jonathan Blackman, Hamish Duncan Morrison, Nicholas Turner, Amanda Heslegrave, Elizabeth Coulthard

Abstract read
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In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victoria Grace GabbBristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-7688-766X
Jonathan BlackmanBristol Medical School, University of Bristol, Bristol, UK.
Hamish Duncan MorrisonBristol Medical School, University of Bristol, Bristol, UK.
Nicholas TurnerBristol Medical School, University of Bristol, Bristol, UK.
Amanda HeslegraveInstitute of Neurology, University College London, London, UK.
Elizabeth CoulthardBristol Medical School, University of Bristol, Bristol, UK.

Funding

Alzheimer's Research UKBRACEBristol and Weston Hospitals CharityDavid Telling Charitable TrustDon Thoburn Memorial ScholarshipMargaret Jost FellowshipNIHR Bristol Biomedical Research CentreS Scobie and A Graham
6 · The paper itself

Abstract

introductionObjective sleep disturbances, including short and fragmented sleep, are observed in neurodegenerative diseases. However, subjective sleep disturbances are inconsistently reported. Improved understanding of objective and subjective sleep estimation is needed to tailor sleep interventions.

methodsBaseline subjective habitual sleep was compared to objective sleep measured by actigraphy averaged over 8 weeks in 20 patients with mild cognitive impairment (MCI) or dementia due to Alzheimer's disease (AD) or Lewy body disease (LBD) and 20 healthy older adults. Discrepancies between objective and subjective sleep parameters were used to predict cohort membership (AD, LBD, or control).

resultsParticipants with AD and LBD estimated lower sleep disturbance than actigraphy. Subjective sleep quality was poorest in LBD and highest in AD. Subjective sleep and subjective-objective sleep discrepancy discriminated between cohorts with 80% accuracy. DISCUSSION: Subjective and objective sleep differ and both should be measured in MCI and dementia. Sleep discrepancy may have diagnostic utility.

Indexed as

Alzheimer DiseaseLewy Body DiseaseSleepSleep Wake DisordersActigraphyAgedAged, 80 and overCognitive DysfunctionFemaleHumansMaleactigraphyAlzheimer's diseasedementiaEEGelectroencephalographyLewy body diseaseobjectiveolder adultssleepsleep discrepancysubjective

Identifiers

PMID42026650
PMCPMC13106027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.